Sequential catalytic reactions for the synthesis of benzofulvenes using an iridium complex with dual function

Kyoji Tsuchikama; Mitsugu Kasagawa; Kohei Endo; Takanori Shibata

doi:10.1055/s-0029-1218575

Sequential catalytic reactions for the synthesis of benzofulvenes using an iridium complex with dual function

Kyoji Tsuchikama, Mitsugu Kasagawa, Kohei Endo, Takanori Shibata^*

^*Corresponding author for this work

School of Advanced Science and Engineering

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Abstract

The cationic iridium complex ([Ir(cod)₂]OTf + racBINAP) efficiently catalyzed a sequential process of ortho-C-H bond functionalization, cyclization and dehydration, leading to a concise preparation of 1 -methylene indene (benzofulvene) derivatives. The iridium complex operated as a catalyst in the ortho-C-H bond alkenylation of aryl ketones with alkynes and as a Lewis acid catalyst in the cyclization of the alkenylated product and the subsequent dehydration.

Original language	English
Pages (from-to)	97-100
Number of pages	4
Journal	Synlett
Issue number	1
DOIs	https://doi.org/10.1055/s-0029-1218575
Publication status	Published - 2010 May 6

Keywords

C-H bond functionalization
Catalysis
Cyclization
Indenes
Iridium

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-0029-1218575

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abstract = "The cationic iridium complex ([Ir(cod)2]OTf + racBINAP) efficiently catalyzed a sequential process of ortho-C-H bond functionalization, cyclization and dehydration, leading to a concise preparation of 1 -methylene indene (benzofulvene) derivatives. The iridium complex operated as a catalyst in the ortho-C-H bond alkenylation of aryl ketones with alkynes and as a Lewis acid catalyst in the cyclization of the alkenylated product and the subsequent dehydration.",

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author = "Kyoji Tsuchikama and Mitsugu Kasagawa and Kohei Endo and Takanori Shibata",

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doi = "10.1055/s-0029-1218575",

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T1 - Sequential catalytic reactions for the synthesis of benzofulvenes using an iridium complex with dual function

AU - Tsuchikama, Kyoji

AU - Kasagawa, Mitsugu

AU - Endo, Kohei

AU - Shibata, Takanori

PY - 2010/5/6

Y1 - 2010/5/6

N2 - The cationic iridium complex ([Ir(cod)2]OTf + racBINAP) efficiently catalyzed a sequential process of ortho-C-H bond functionalization, cyclization and dehydration, leading to a concise preparation of 1 -methylene indene (benzofulvene) derivatives. The iridium complex operated as a catalyst in the ortho-C-H bond alkenylation of aryl ketones with alkynes and as a Lewis acid catalyst in the cyclization of the alkenylated product and the subsequent dehydration.

AB - The cationic iridium complex ([Ir(cod)2]OTf + racBINAP) efficiently catalyzed a sequential process of ortho-C-H bond functionalization, cyclization and dehydration, leading to a concise preparation of 1 -methylene indene (benzofulvene) derivatives. The iridium complex operated as a catalyst in the ortho-C-H bond alkenylation of aryl ketones with alkynes and as a Lewis acid catalyst in the cyclization of the alkenylated product and the subsequent dehydration.

KW - C-H bond functionalization

KW - Catalysis

KW - Cyclization

KW - Indenes

KW - Iridium

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JO - Synlett

JF - Synlett

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ER -

Sequential catalytic reactions for the synthesis of benzofulvenes using an iridium complex with dual function

Abstract

Keywords

ASJC Scopus subject areas

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