Serum interleukin-18 levels are associated with physical activity in Japanese men

Kanae Oda; Nobuyuki Miyatake; Noriko Sakano; Takeshi Saito; Motohiko Miyachi; Izumi Tabata; Takeyuki Numata

doi:10.1371/journal.pone.0081497

Serum interleukin-18 levels are associated with physical activity in Japanese men

Kanae Oda, Nobuyuki Miyatake, Noriko Sakano, Takeshi Saito, Motohiko Miyachi, Izumi Tabata, Takeyuki Numata

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Objective: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. Methods: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. Results: Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by ∑[metabolic equivalents x h per week (METs·h/w)]was significantly and negatively correlated with serum IL-18 levels (r = -0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. Conclusion: Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.

Original language	English
Article number	e81497
Journal	PloS one
Volume	8
Issue number	12
DOIs	https://doi.org/10.1371/journal.pone.0081497
Publication status	Published - 2013 Dec 11
Externally published	Yes

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title = "Serum interleukin-18 levels are associated with physical activity in Japanese men",

abstract = "Objective: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. Methods: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. Results: Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by ∑[metabolic equivalents x h per week (METs·h/w)]was significantly and negatively correlated with serum IL-18 levels (r = -0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. Conclusion: Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.",

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T1 - Serum interleukin-18 levels are associated with physical activity in Japanese men

AU - Oda, Kanae

AU - Miyatake, Nobuyuki

AU - Sakano, Noriko

AU - Saito, Takeshi

AU - Miyachi, Motohiko

AU - Tabata, Izumi

AU - Numata, Takeyuki

PY - 2013/12/11

Y1 - 2013/12/11

N2 - Objective: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. Methods: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. Results: Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by ∑[metabolic equivalents x h per week (METs·h/w)]was significantly and negatively correlated with serum IL-18 levels (r = -0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. Conclusion: Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.

AB - Objective: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. Methods: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. Results: Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by ∑[metabolic equivalents x h per week (METs·h/w)]was significantly and negatively correlated with serum IL-18 levels (r = -0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. Conclusion: Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.

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Serum interleukin-18 levels are associated with physical activity in Japanese men

Abstract

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