Shape-memory surface with dynamically tunable nano-geometry activated by body heat

Mitsuhiro Ebara, Koichiro Uto, Naokazu Idota, John M. Hoffman, Takao Aoyagi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

171 Citations (Scopus)


Shape-memory surfaces with on-demand, tunable nanopatterns are developed to observe time dependent changes in cell alignment using temperature-responsive poly(Ïμ-caprolactone) (PCL) films. Temporary grooved nanopatterns are easily programmed on the films and triggered to transition quickly to permanent surface patterns by the application of body heat. A time-dependent cytoskeleton remodeling is also observed under biologically relevant conditions.

Original languageEnglish
Pages (from-to)273-278
Number of pages6
JournalAdvanced Materials
Issue number2
Publication statusPublished - 2012 Jan 10
Externally publishedYes


  • biomedical applications
  • polymeric materials
  • shape-memory materials
  • stimuli-responsive materials

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


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