Space-time finite element computation of arterial fluid-structure interactions with patient-specific data

Kenji Takizawa, Jason Christopher, Tayfun E. Tezduyar*, Sunil Sathe

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

111 Citations (Scopus)


The stabilized space-time fluid-structure interaction (SSTFSI) technique developed by the team for advanced flow simulation and modeling is applied to the computation of arterial fluid-structure interaction (FSI) with patient-specific data. The SSTFSI technique is based on the deforming-spatial-domain/stabilized space-time formulation and is supplemented with a number of special techniques developed for arterial FSI. These include a recipe for pre-FSI computations that improve the convergence of the FSI computations, using an estimated zero-pressure arterial geometry, layers of refined fluid mechanics mesh near the arterial walls, and a special mapping technique for specifying the velocity profile at an inflow boundary with non-circular shape. In the test computations reported here, we focus on a patient-specific middle cerebral artery segment with aneurysm, where the arterial geometry is based on computed tomography images.

Original languageEnglish
Pages (from-to)101-116
Number of pages16
JournalInternational Journal for Numerical Methods in Biomedical Engineering
Issue number1
Publication statusPublished - 2010 Jan
Externally publishedYes


  • Cardiovascular fluid mechanics
  • Cerebral aneurysms
  • Fluid-structure interactions
  • Hyperelastic material
  • Patient-specific data
  • Space-time methods

ASJC Scopus subject areas

  • Software
  • Biomedical Engineering
  • Modelling and Simulation
  • Molecular Biology
  • Computational Theory and Mathematics
  • Applied Mathematics


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