Stereochemical Assignment of the 36-Membered Macrolide Ring Portion of Poecillastrin C

Raku Irie; Yuki Hitora; Ryuichi Watanabe; Hugh Clark; Yu Suyama; Shinji Sekiya; Toshiyuki Suzuki; Kentaro Takada; Shigeki Matsunaga; Seijiro Hosokawa; Masato Oikawa

doi:10.1021/acs.orglett.4c01632

Stereochemical Assignment of the 36-Membered Macrolide Ring Portion of Poecillastrin C

Raku Irie^*, Yuki Hitora, Ryuichi Watanabe, Hugh Clark, Yu Suyama, Shinji Sekiya, Toshiyuki Suzuki, Kentaro Takada, Shigeki Matsunaga, Seijiro Hosokawa, Masato Oikawa

^*Corresponding author for this work

School of Advanced Science and Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Absolute configuration at 12 stereocenters in the 36-membered macrocyclic ring portion of poecillastrin C (1) was disclosed by chemical degradation and NMR analyses of 1, chemical synthesis, and molecular modeling techniques.

Original language	English
Pages (from-to)	5290-5294
Number of pages	5
Journal	Organic Letters
Volume	26
Issue number	25
DOIs	https://doi.org/10.1021/acs.orglett.4c01632
Publication status	Published - 2024 Jun 28

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/acs.orglett.4c01632

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title = "Stereochemical Assignment of the 36-Membered Macrolide Ring Portion of Poecillastrin C",

abstract = "Absolute configuration at 12 stereocenters in the 36-membered macrocyclic ring portion of poecillastrin C (1) was disclosed by chemical degradation and NMR analyses of 1, chemical synthesis, and molecular modeling techniques.",

author = "Raku Irie and Yuki Hitora and Ryuichi Watanabe and Hugh Clark and Yu Suyama and Shinji Sekiya and Toshiyuki Suzuki and Kentaro Takada and Shigeki Matsunaga and Seijiro Hosokawa and Masato Oikawa",

note = "Publisher Copyright: {\textcopyright} 2024 American Chemical Society.",

year = "2024",

month = jun,

day = "28",

doi = "10.1021/acs.orglett.4c01632",

language = "English",

volume = "26",

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journal = "Organic Letters",

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T1 - Stereochemical Assignment of the 36-Membered Macrolide Ring Portion of Poecillastrin C

AU - Irie, Raku

AU - Hitora, Yuki

AU - Watanabe, Ryuichi

AU - Clark, Hugh

AU - Suyama, Yu

AU - Sekiya, Shinji

AU - Suzuki, Toshiyuki

AU - Takada, Kentaro

AU - Matsunaga, Shigeki

AU - Hosokawa, Seijiro

AU - Oikawa, Masato

PY - 2024/6/28

Y1 - 2024/6/28

N2 - Absolute configuration at 12 stereocenters in the 36-membered macrocyclic ring portion of poecillastrin C (1) was disclosed by chemical degradation and NMR analyses of 1, chemical synthesis, and molecular modeling techniques.

AB - Absolute configuration at 12 stereocenters in the 36-membered macrocyclic ring portion of poecillastrin C (1) was disclosed by chemical degradation and NMR analyses of 1, chemical synthesis, and molecular modeling techniques.

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U2 - 10.1021/acs.orglett.4c01632

DO - 10.1021/acs.orglett.4c01632

M3 - Article

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AN - SCOPUS:85196015125

SN - 1523-7060

VL - 26

SP - 5290

EP - 5294

JO - Organic Letters

JF - Organic Letters

IS - 25

ER -

Stereochemical Assignment of the 36-Membered Macrolide Ring Portion of Poecillastrin C

Abstract

ASJC Scopus subject areas

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