Stereospecific transformation of a chiral pyrimidyl alkanol into L-valine

Kenso Soai; Shigehisa Tanji; Yasutaka Kodaka; Takanori Shibata

Stereospecific transformation of a chiral pyrimidyl alkanol into L-valine

Kenso Soai^*, Shigehisa Tanji, Yasutaka Kodaka, Takanori Shibata

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A chiral pyrimidyl alkanol with high enantiomeric excess is transformed into L-valine with high e.e. by a notable oxidative cleavage of pyrimidine ring using ruthenium oxide as a key step. This process would correlate natural α-amino acids with a chiral pyrimidyl alkanol, which is reported to possess an asymmetric autocatalytic activity with amplification of e.e.

Original language	English
Pages (from-to)	241-243
Number of pages	3
Journal	Enantiomer
Volume	3
Issue number	3
Publication status	Published - 1998 Nov 24
Externally published	Yes

Keywords

Amino acid
Pyrimidyl alkanol
Stereospecific
Valine

ASJC Scopus subject areas

Chemistry(all)
Biochemistry
Biochemistry, Genetics and Molecular Biology(all)
Organic Chemistry

Cite this

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title = "Stereospecific transformation of a chiral pyrimidyl alkanol into L-valine",

abstract = "A chiral pyrimidyl alkanol with high enantiomeric excess is transformed into L-valine with high e.e. by a notable oxidative cleavage of pyrimidine ring using ruthenium oxide as a key step. This process would correlate natural α-amino acids with a chiral pyrimidyl alkanol, which is reported to possess an asymmetric autocatalytic activity with amplification of e.e.",

keywords = "Amino acid, Pyrimidyl alkanol, Stereospecific, Valine",

author = "Kenso Soai and Shigehisa Tanji and Yasutaka Kodaka and Takanori Shibata",

year = "1998",

month = nov,

day = "24",

language = "English",

volume = "3",

pages = "241--243",

journal = "Enantiomer",

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publisher = "Taylor and Francis Ltd.",

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T1 - Stereospecific transformation of a chiral pyrimidyl alkanol into L-valine

AU - Soai, Kenso

AU - Tanji, Shigehisa

AU - Kodaka, Yasutaka

AU - Shibata, Takanori

PY - 1998/11/24

Y1 - 1998/11/24

N2 - A chiral pyrimidyl alkanol with high enantiomeric excess is transformed into L-valine with high e.e. by a notable oxidative cleavage of pyrimidine ring using ruthenium oxide as a key step. This process would correlate natural α-amino acids with a chiral pyrimidyl alkanol, which is reported to possess an asymmetric autocatalytic activity with amplification of e.e.

AB - A chiral pyrimidyl alkanol with high enantiomeric excess is transformed into L-valine with high e.e. by a notable oxidative cleavage of pyrimidine ring using ruthenium oxide as a key step. This process would correlate natural α-amino acids with a chiral pyrimidyl alkanol, which is reported to possess an asymmetric autocatalytic activity with amplification of e.e.

KW - Amino acid

KW - Pyrimidyl alkanol

KW - Stereospecific

KW - Valine

UR - http://www.scopus.com/inward/record.url?scp=0031772675&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031772675&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0031772675

SN - 1024-2430

VL - 3

SP - 241

EP - 243

JO - Enantiomer

JF - Enantiomer

IS - 3

ER -

Stereospecific transformation of a chiral pyrimidyl alkanol into L-valine

Abstract

Keywords

ASJC Scopus subject areas

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