TY - JOUR
T1 - Structural and functional analyses of proteins involved in translation, DNA recombination, chromosome architecture, and signal transduction
AU - Kurumizaka, Hitoshi
AU - Yokoyama, Shigeyuki
PY - 2002
Y1 - 2002
N2 - Structural biology, in which the mechanisms of biological systems are elucidated by the three-dimensional structures of biomacromolecules, such as proteins and nucleic acids, is rapidly progressing. An aim of our research is to establish a novel strategy for understanding the functions of biomacromolecules through structural biology as well as biochemistry, molecular biology, and cell biology. In this article, we discuss our current progress in structural biology toward understanding the mechanisms of translation, DNA recombination, centromere architecture, and signal transduction.
AB - Structural biology, in which the mechanisms of biological systems are elucidated by the three-dimensional structures of biomacromolecules, such as proteins and nucleic acids, is rapidly progressing. An aim of our research is to establish a novel strategy for understanding the functions of biomacromolecules through structural biology as well as biochemistry, molecular biology, and cell biology. In this article, we discuss our current progress in structural biology toward understanding the mechanisms of translation, DNA recombination, centromere architecture, and signal transduction.
UR - http://www.scopus.com/inward/record.url?scp=77957058318&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77957058318&partnerID=8YFLogxK
U2 - 10.1016/S0921-0423(02)80051-X
DO - 10.1016/S0921-0423(02)80051-X
M3 - Article
AN - SCOPUS:77957058318
SN - 0921-0423
VL - 22
SP - 169
EP - 180
JO - Progress in Biotechnology
JF - Progress in Biotechnology
IS - C
ER -