Abstract
(Chemical Equation Presented) From aldehydes to allenic alcohols: Studies into the asymmetric catalysis of the Nozaki-Hiyama allenylation are described. Ligand 1a is effective for the enantioselective allenylations of various aldehydes, with the generation of products with ee values ranging from 72-83%. The products can be easily desilylated or used as allenylsilanes. DIPEA = diisopropylethylamine, DMI = 1,3-dimethyl-2-imidazolidinone, DMS = dimethylsilyl, TMS = trimethylsilyl.
| Original language | English |
|---|---|
| Pages (from-to) | 252-255 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 45 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2005 Dec 23 |
Keywords
- Allenes
- Allenic alcohols
- Asymmetric catalysis
- Chromium
- Enantioselectivity
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)