Switchable substrates for analyzing and engineering cellular functions

Jun Nakanishi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Cellular activity is highly dependent on the extracellular environment, which is composed of surrounding cells and extracellular matrices. This focus review summarizes recent advances in chemically and physically engineered switchable substrates designed to control such cellular microenvironments by application of an external stimulus. Special attention is given to their molecular design, switching strategies, and representative examples for bioanalytical and biomedical applications.

Original languageEnglish
Pages (from-to)406-417
Number of pages12
JournalChemistry - An Asian Journal
Issue number2
Publication statusPublished - 2014 Feb 1
Externally publishedYes


  • cell adhesion
  • cell migration
  • electrochemistry
  • photochemistry
  • tissue engineering

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry


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