Synthesis and kinetic cyclisation of quinine-derived oligomers

Stuart J. Rowan; Paul A. Brady; Jeremy K M Sanders

doi:10.1016/0040-4039(96)01263-4

Synthesis and kinetic cyclisation of quinine-derived oligomers

Stuart J. Rowan, Paul A. Brady, Jeremy K M Sanders^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

The synthesis and kinetic cyclisations of a series of linear quinine oligomers are described. The distribution of cyclic oligomers is different from that observed in the corresponding thermodynamic cyclisation: cyclic tetramer is observed in the kinetic cyclisations, indicating that its absence under thermodynamic conditions is not due to any kinetic barrier to its formation.

Original language	English
Pages (from-to)	6013-6016
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	33
DOIs	https://doi.org/10.1016/0040-4039(96)01263-4
Publication status	Published - 1996 Aug 12
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Organic Chemistry
Drug Discovery

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10.1016/0040-4039(96)01263-4

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title = "Synthesis and kinetic cyclisation of quinine-derived oligomers",

abstract = "The synthesis and kinetic cyclisations of a series of linear quinine oligomers are described. The distribution of cyclic oligomers is different from that observed in the corresponding thermodynamic cyclisation: cyclic tetramer is observed in the kinetic cyclisations, indicating that its absence under thermodynamic conditions is not due to any kinetic barrier to its formation.",

author = "Rowan, {Stuart J.} and Brady, {Paul A.} and Sanders, {Jeremy K M}",

year = "1996",

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T1 - Synthesis and kinetic cyclisation of quinine-derived oligomers

AU - Rowan, Stuart J.

AU - Brady, Paul A.

AU - Sanders, Jeremy K M

PY - 1996/8/12

Y1 - 1996/8/12

N2 - The synthesis and kinetic cyclisations of a series of linear quinine oligomers are described. The distribution of cyclic oligomers is different from that observed in the corresponding thermodynamic cyclisation: cyclic tetramer is observed in the kinetic cyclisations, indicating that its absence under thermodynamic conditions is not due to any kinetic barrier to its formation.

AB - The synthesis and kinetic cyclisations of a series of linear quinine oligomers are described. The distribution of cyclic oligomers is different from that observed in the corresponding thermodynamic cyclisation: cyclic tetramer is observed in the kinetic cyclisations, indicating that its absence under thermodynamic conditions is not due to any kinetic barrier to its formation.

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U2 - 10.1016/0040-4039(96)01263-4

DO - 10.1016/0040-4039(96)01263-4

M3 - Article

AN - SCOPUS:0030581328

SN - 0040-4039

VL - 37

SP - 6013

EP - 6016

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 33

ER -

Synthesis and kinetic cyclisation of quinine-derived oligomers

Abstract

ASJC Scopus subject areas

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