Synthesis of β-amino ketones by iridium(III)-catalyzed direct-Mannich reaction

Shunsuke Sueki, Takeyuki Igarashi, Takayuki Nakajima, Isao Shimizu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


The direct-Mannich reaction of ketones 1, aldehydes 2, and anilines 3 was studied using catalytic amount of transition-metal complexes. The trivalent iridium complex, [IrCl2(H)(COd)]2, catalyzed the direct-Mannich reaction effectively to give various β-amino kenotes in good yields under mild conditions.

Original languageEnglish
Pages (from-to)682-683
Number of pages2
JournalChemistry Letters
Issue number6
Publication statusPublished - 2006 Jun 5

ASJC Scopus subject areas

  • Chemistry(all)


Dive into the research topics of 'Synthesis of β-amino ketones by iridium(III)-catalyzed direct-Mannich reaction'. Together they form a unique fingerprint.

Cite this