Technical note: Short-time sequential high-energy gamma photon imaging using list-mode data acquisition system for high-dose-rate brachytherapy

Jura Nagata, Seiichi Yamamoto*, Takuya Yabe, Katsunori Yogo, Kohei Nakanishi, Yumiko Noguchi, Kuniyasu Okudaira, Kei Kamada, Akira Yoshikawa, Jun Kataoka

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

1 Citation (Scopus)

Abstract

Purpose: Measurement of the dwell time and moving speed of a high-activity iridium-192 (Ir-192) source used for high-dose-rate (HDR) brachytherapy is important for estimating the precise dose delivery to a tumor. For this purpose, we used a cerium-doped yttrium aluminum perovskite (YA1O3:YAP(Ce)) gamma camera system, combined with a list-mode data acquisition system that can acquire short-time sequential images, and measured the dwell times and moving speeds of the Ir-192 source. Methods: Gamma photon imaging was conducted using the gamma camera in list mode for the Ir-192 source of HDR brachytherapy with fixed dwell times and positions. The acquired list-mode images were sorted to millisecond-order interval time sequential images to evaluate the dwell time at each position. Time count rate curves were derived to calculate the dwell time at each source position and moving speed of the source. Results: We could measure the millisecond-order time sequential images for the Ir-192 source. The measured times for the preset dwell times of 2 s and 10 s were 1.98 to 2.00 s full width at half maximum (FWHM) and 10.0 s FWHM, respectively. The dwell times at the first dwell position were larger than those at other positions. We also measured the moving speeds of the source after the dwells while moving back to the afterloader and found the speed increased with the distance from the edge of the field of view to the last dwell position. Conclusion: We conclude that millisecond-order time sequential imaging of the Ir-192 source is possible by using a gamma camera and is useful for evaluating the dwell times and moving speeds of the Ir-192 source.

Original languageEnglish
Pages (from-to)7703-7714
Number of pages12
JournalMedical Physics
Volume49
Issue number12
DOIs
Publication statusPublished - 2022 Dec

Keywords

  • HDR brachytherapy
  • Ir-192 source
  • YAP(Ce)
  • gamma camera
  • list mode
  • time sequential imaging

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

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