Temperature-responsiveness and antimicrobial properties of CNT-PNIPAM hybrid brush films

Katrina D. Pangilinan; Catherine M. Santos; Nicel C. Estillore; Debora F. Rodrigues; Rigoberto C. Advincula

doi:10.1002/macp.201200464

Temperature-responsiveness and antimicrobial properties of CNT-PNIPAM hybrid brush films

Katrina D. Pangilinan, Catherine M. Santos, Nicel C. Estillore, Debora F. Rodrigues, Rigoberto C. Advincula^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Temperature-responsive carbon nanotube (CNT)/poly(N-isopropylacrylamide) (PNIPAM) hybrid brush films were prepared by combining the layer-by-layer and surface-initiated polymerization (LbL-SIP) techniques. Atom transfer radical polymerization (ATRP) is employed for the preparation of PNIPAM polymer brushes. Antibacterial activity of the CNT/PNIPAM films are investigated against Exiguobacterium sp. AT1b and Exiguobacterium sibiricum strains. Dead assay results show high microbial inactivation on coated surfaces with CNT films, while very low microbial inactivation is observed in PNIPAM films at all temperatures tested. The CNT-PNIPAM films, on the other hand, have antibacterial properties below 32 °C, which is below the lower critical solution temperature (LCST), but allows biofilm formation above the LCST. Carbon nanotubes incorporated via layer-by-layer assembly in ultra-thin films with temperature-sensitive polymer brushes exhibit unique antibacterial properties tunable with temperature. These hybrid films are useful for actively preventing biofilm formation at various temperature conditions and can be employed as smart coatings.

Original language	English
Pages (from-to)	464-469
Number of pages	6
Journal	Macromolecular Chemistry and Physics
Volume	214
Issue number	4
DOIs	https://doi.org/10.1002/macp.201200464
Publication status	Published - 2013 Feb 25
Externally published	Yes

Keywords

antibacterial
carbon nanotubes
poly(N-isopropylacrylamide)
polymerizations

ASJC Scopus subject areas

Condensed Matter Physics
Physical and Theoretical Chemistry
Polymers and Plastics
Organic Chemistry
Materials Chemistry

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title = "Temperature-responsiveness and antimicrobial properties of CNT-PNIPAM hybrid brush films",

abstract = "Temperature-responsive carbon nanotube (CNT)/poly(N-isopropylacrylamide) (PNIPAM) hybrid brush films were prepared by combining the layer-by-layer and surface-initiated polymerization (LbL-SIP) techniques. Atom transfer radical polymerization (ATRP) is employed for the preparation of PNIPAM polymer brushes. Antibacterial activity of the CNT/PNIPAM films are investigated against Exiguobacterium sp. AT1b and Exiguobacterium sibiricum strains. Dead assay results show high microbial inactivation on coated surfaces with CNT films, while very low microbial inactivation is observed in PNIPAM films at all temperatures tested. The CNT-PNIPAM films, on the other hand, have antibacterial properties below 32 °C, which is below the lower critical solution temperature (LCST), but allows biofilm formation above the LCST. Carbon nanotubes incorporated via layer-by-layer assembly in ultra-thin films with temperature-sensitive polymer brushes exhibit unique antibacterial properties tunable with temperature. These hybrid films are useful for actively preventing biofilm formation at various temperature conditions and can be employed as smart coatings.",

keywords = "antibacterial, carbon nanotubes, poly(N-isopropylacrylamide), polymerizations",

author = "Pangilinan, {Katrina D.} and Santos, {Catherine M.} and Estillore, {Nicel C.} and Rodrigues, {Debora F.} and Advincula, {Rigoberto C.}",

year = "2013",

month = feb,

day = "25",

doi = "10.1002/macp.201200464",

language = "English",

volume = "214",

pages = "464--469",

journal = "Macromolecular Chemistry and Physics",

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T1 - Temperature-responsiveness and antimicrobial properties of CNT-PNIPAM hybrid brush films

AU - Pangilinan, Katrina D.

AU - Santos, Catherine M.

AU - Estillore, Nicel C.

AU - Rodrigues, Debora F.

AU - Advincula, Rigoberto C.

PY - 2013/2/25

Y1 - 2013/2/25

N2 - Temperature-responsive carbon nanotube (CNT)/poly(N-isopropylacrylamide) (PNIPAM) hybrid brush films were prepared by combining the layer-by-layer and surface-initiated polymerization (LbL-SIP) techniques. Atom transfer radical polymerization (ATRP) is employed for the preparation of PNIPAM polymer brushes. Antibacterial activity of the CNT/PNIPAM films are investigated against Exiguobacterium sp. AT1b and Exiguobacterium sibiricum strains. Dead assay results show high microbial inactivation on coated surfaces with CNT films, while very low microbial inactivation is observed in PNIPAM films at all temperatures tested. The CNT-PNIPAM films, on the other hand, have antibacterial properties below 32 °C, which is below the lower critical solution temperature (LCST), but allows biofilm formation above the LCST. Carbon nanotubes incorporated via layer-by-layer assembly in ultra-thin films with temperature-sensitive polymer brushes exhibit unique antibacterial properties tunable with temperature. These hybrid films are useful for actively preventing biofilm formation at various temperature conditions and can be employed as smart coatings.

AB - Temperature-responsive carbon nanotube (CNT)/poly(N-isopropylacrylamide) (PNIPAM) hybrid brush films were prepared by combining the layer-by-layer and surface-initiated polymerization (LbL-SIP) techniques. Atom transfer radical polymerization (ATRP) is employed for the preparation of PNIPAM polymer brushes. Antibacterial activity of the CNT/PNIPAM films are investigated against Exiguobacterium sp. AT1b and Exiguobacterium sibiricum strains. Dead assay results show high microbial inactivation on coated surfaces with CNT films, while very low microbial inactivation is observed in PNIPAM films at all temperatures tested. The CNT-PNIPAM films, on the other hand, have antibacterial properties below 32 °C, which is below the lower critical solution temperature (LCST), but allows biofilm formation above the LCST. Carbon nanotubes incorporated via layer-by-layer assembly in ultra-thin films with temperature-sensitive polymer brushes exhibit unique antibacterial properties tunable with temperature. These hybrid films are useful for actively preventing biofilm formation at various temperature conditions and can be employed as smart coatings.

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KW - polymerizations

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Temperature-responsiveness and antimicrobial properties of CNT-PNIPAM hybrid brush films

Abstract

Keywords

ASJC Scopus subject areas

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