The enhanced 32P labeling of CDP-diacylglycerol in c-myc gene expressed human kidney cancer cells

Yoshinobu Kubota; Taro Shuin; Masahiro Yao; Hiroko Inoue; Tohru Yoshioka

doi:10.1016/0014-5793(87)81577-6

The enhanced ³²P labeling of CDP-diacylglycerol in c-myc gene expressed human kidney cancer cells

Yoshinobu Kubota, Taro Shuin, Masahiro Yao, Hiroko Inoue, Tohru Yoshioka^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Correlation between c-myc gene expression and phosphatidylinositol (PI) metabolism was studied using seven human kidney cancer cell lines. We found that the exceptional incorporation of ³²P into CDP-diacyl-glycerol (CDP-DG) was observed in only two cell lines, in which c-myc expression was increased among seven cell lines tested. In these two cell lines, PI was also labeled. The other five cell lines indicated the accumulation of radioactive PI, whereas CDP- DG was unlabeled.

Original language	English
Pages (from-to)	159-162
Number of pages	4
Journal	FEBS Letters
Volume	212
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(87)81577-6
Publication status	Published - 1987 Feb 9

Keywords

(Kidney cancer cell)
c-myc gene
CDP-diacylglycerol
Phosphatidylinositol metabolism

ASJC Scopus subject areas

Biochemistry
Biophysics
Molecular Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/0014-5793(87)81577-6

Cite this

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title = "The enhanced 32P labeling of CDP-diacylglycerol in c-myc gene expressed human kidney cancer cells",

abstract = "Correlation between c-myc gene expression and phosphatidylinositol (PI) metabolism was studied using seven human kidney cancer cell lines. We found that the exceptional incorporation of 32P into CDP-diacyl-glycerol (CDP-DG) was observed in only two cell lines, in which c-myc expression was increased among seven cell lines tested. In these two cell lines, PI was also labeled. The other five cell lines indicated the accumulation of radioactive PI, whereas CDP- DG was unlabeled.",

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T1 - The enhanced 32P labeling of CDP-diacylglycerol in c-myc gene expressed human kidney cancer cells

AU - Kubota, Yoshinobu

AU - Shuin, Taro

AU - Yao, Masahiro

AU - Inoue, Hiroko

AU - Yoshioka, Tohru

PY - 1987/2/9

Y1 - 1987/2/9

N2 - Correlation between c-myc gene expression and phosphatidylinositol (PI) metabolism was studied using seven human kidney cancer cell lines. We found that the exceptional incorporation of 32P into CDP-diacyl-glycerol (CDP-DG) was observed in only two cell lines, in which c-myc expression was increased among seven cell lines tested. In these two cell lines, PI was also labeled. The other five cell lines indicated the accumulation of radioactive PI, whereas CDP- DG was unlabeled.

AB - Correlation between c-myc gene expression and phosphatidylinositol (PI) metabolism was studied using seven human kidney cancer cell lines. We found that the exceptional incorporation of 32P into CDP-diacyl-glycerol (CDP-DG) was observed in only two cell lines, in which c-myc expression was increased among seven cell lines tested. In these two cell lines, PI was also labeled. The other five cell lines indicated the accumulation of radioactive PI, whereas CDP- DG was unlabeled.

KW - (Kidney cancer cell)

KW - c-myc gene

KW - CDP-diacylglycerol

KW - Phosphatidylinositol metabolism

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