@article{a5d984cad98c4f529c747e639d3fa3fc,
title = "The genome of Chenopodium quinoa",
abstract = "Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome-contact and genetic maps. We also report the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identification of sub-genomes in quinoa, and reduced-coverage genome sequences for 22 other samples of the allotetraploid goosefoot complex. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and a premature stop codon in sweet quinoa strains. These genomic resources are an important first step towards the genetic improvement of quinoa.",
author = "Jarvis, {David E.} and Ho, {Yung Shwen} and Lightfoot, {Damien J.} and Schm{\"o}ckel, {Sandra M.} and Bo Li and Borm, {Theo J.A.} and Hajime Ohyanagi and Katsuhiko Mineta and Michell, {Craig T.} and Noha Saber and Kharbatia, {Najeh M.} and Rupper, {Ryan R.} and Sharp, {Aaron R.} and Nadine Dally and Boughton, {Berin A.} and Woo, {Yong H.} and Ge Gao and Schijlen, {Elio G.W.M.} and Xiujie Guo and Momin, {Afaque A.} and S{\'o}nia Negr{\~a}o and Salim Al-Babili and Christoph Gehring and Ute Roessner and Christian Jung and Kevin Murphy and Arold, {Stefan T.} and Takashi Gojobori and Linden, {C. Gerard Van Der} and {Van Loo}, {Eibertus N.} and Jellen, {Eric N.} and Maughan, {Peter J.} and Mark Tester",
note = "Funding Information: Research reported in this publication was supported by the King Abdullah University of Science and Technology (KAUST), by USDA/NIFAREEIS grant #2012-51300-20100 (WSU/BYU), by NSF grant #1339412, and by a grant from the German Research Foundation, DFG (grant no. JU205/24-1). We thank T. Ramaraj from the National Center for Genomic Resources (Santa Fe) for his bioinformatics assistance, O. Mohammed Eid Alharbi at the KAUSTImaging and Characterization Laboratory for generating SEM images, K. Zemmouri at the KAUST Greenhouse for plant care, and H. Ho (Heno) Hwang and I. D. Gromicho at the KAUST Academic Writing Department for assistance with quinoa illustrations and photographs. We also thank H. torchov? F. Morton, D. Bertero, F. Fuentes and D. Brenner of USDA-ARS-NPGS for their assistance in providing seeds. Publisher Copyright: {\textcopyright} 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.",
year = "2017",
month = feb,
day = "16",
doi = "10.1038/nature21370",
language = "English",
volume = "542",
pages = "307--312",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7641",
}
