The multiple sample injector using improved sheath flow to prevent sample dilution

Masaki Kanai*, Shingo Ikeda, Junichi Tanaka, Jeung Sang Go, Hiroaki Nakanishi, Shuichi Shoji

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

11 Citations (Scopus)


This paper presents a sheath flow multiple sample injector that realizes concentration-conservative sample injection. Stepwise flow is used to reduce the dilution of the sample reagent. Based on the CFD simulation results, it is estimated that sample reagent is diluted to 94% in a conventional sample injector. With stepwise flow, however, the level of dilution is reduced and the average concentration is estimated to be near 100%. For the experiment evaluation, a sample injector is fabricated and the sample injection using stepwise flow is visualized using a fluorescent measuring system. The accuracy of the injected sample volume and the feasibility of multiple sample injection are evaluated based on the experiment results.

Original languageEnglish
Pages (from-to)32-36
Number of pages5
JournalSensors and Actuators, A: Physical
Issue number1
Publication statusPublished - 2004 Mar 1
EventMicromechanics Section of Sensors and Actuators, based on - Kyoto, Japan
Duration: 2003 Jan 192003 Jan 23


  • CFD simulation
  • Sample injector
  • Sheath flow

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering


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