Three-dimensional (3D) dose distribution measurements of proton beam using a glass plate

Ryo Horita, Seiichi Yamamoto, Katsunori Yogo, Masataka Komori, Toshiyuki Toshito

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


The measurements of the three-dimensional (3D) dose distribution of proton beams in water are critical for proton therapy for quality assessment (QA). Although ionization chambers are commonly used for this purpose, such measurements take a long time to calculate precise 3D dose distribution. To solve this problem, we measured 3D dose distributions using a glass plate. We placed a 1-mm thick float glass plate on the upper inside of a black box with a water tank set above the float glass plate outside the black box and irradiated the proton beam to the water tank from the upper side. The attenuated proton beam by water in the tank was detected by the float glass plate and a scintillation image was formed in the plate. The image was reflected by a first-surface mirror set below the float glass plate and detected by a cooled charge-coupled device (CCD) camera from the side. We changed the water depths in the tank and measured the scintillation images at each depth. Then we calculated the 3D scintillation images from the measured images by stacking them in the depth direction. Measurements were made for 71.2- and 100-MeV proton pencil beams and a spread-out Bragg peak (SOBP) using the imaging system. From the images, we successfully formed 3D scintillation images without quenching. The depth profiles measured from the scintillation images showed almost identical distribution with those measured by the ionization chamber within a maximum difference less than 5%. The lateral profiles were also almost identical within width differences less than 2 mm. We conclude that our proposed method is promising for the 3D dose distribution measurements of proton beams.

Original languageEnglish
Article number045033
JournalBiomedical Physics and Engineering Express
Issue number4
Publication statusPublished - 2019 Jul 12
Externally publishedYes


  • optical imaging
  • proton beam
  • three-dimensional dose distribution

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Physiology
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging
  • Computer Science Applications
  • Health Informatics


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