Total syntheses of (-)-scabronines G and A, and (-)-episcabronine A

Yu Kobayakawa, Masahisa Nakada*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Making scab(ronine)s: The total synthesis of (-)-scabronine G features a highly stereoselective oxidative dearomatization/intramolecular inverse-electron-demand Diels-Alder reaction cascade, and the first total synthesis of (-)-scabronine A comprises a highly stereoselective oxa-Michael/protonation/acetalization cascade. The first total synthesis of (-)-episcabronine A includes another highly stereoselective cascade.

Original languageEnglish
Pages (from-to)7569-7573
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number29
Publication statusPublished - 2013 Jul 15


  • cycloaddition
  • enantioselectivity
  • medium-ring compounds
  • natural products
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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