Total synthesis of palau'amine

Ian B. Seiple; Shun Su; Ian S. Young; Chad A. Lewis; Junichiro Yamaguchi; Phil S. Baran

doi:10.1002/anie.200907112

Total synthesis of palau'amine

Ian B. Seiple, Shun Su, Ian S. Young, Chad A. Lewis, Junichiro Yamaguchi, Phil S. Baran

Research output: Contribution to journal › Article › peer-review

93 Citations (Scopus)

Abstract

(Figure Presented) Worth the wait: The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade reactions, and a remarkable transannular cyclization to secure the unprecedented trans-5,5 ring junction (shown in red).

Original language	English
Pages (from-to)	1095-1098
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	6
DOIs	https://doi.org/10.1002/anie.200907112
Publication status	Published - 2010 Feb 1
Externally published	Yes

Keywords

Axinellamines
Massadine
Palau'amine
Total synthesis

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200907112

Cite this

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title = "Total synthesis of palau'amine",

abstract = "(Figure Presented) Worth the wait: The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade reactions, and a remarkable transannular cyclization to secure the unprecedented trans-5,5 ring junction (shown in red).",

keywords = "Axinellamines, Massadine, Palau'amine, Total synthesis",

author = "Seiple, {Ian B.} and Shun Su and Young, {Ian S.} and Lewis, {Chad A.} and Junichiro Yamaguchi and Baran, {Phil S.}",

year = "2010",

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T1 - Total synthesis of palau'amine

AU - Seiple, Ian B.

AU - Su, Shun

AU - Young, Ian S.

AU - Lewis, Chad A.

AU - Yamaguchi, Junichiro

AU - Baran, Phil S.

PY - 2010/2/1

Y1 - 2010/2/1

N2 - (Figure Presented) Worth the wait: The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade reactions, and a remarkable transannular cyclization to secure the unprecedented trans-5,5 ring junction (shown in red).

AB - (Figure Presented) Worth the wait: The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade reactions, and a remarkable transannular cyclization to secure the unprecedented trans-5,5 ring junction (shown in red).

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KW - Massadine

KW - Palau'amine

KW - Total synthesis

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Total synthesis of palau'amine

Abstract

Keywords

ASJC Scopus subject areas

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