Total synthesis of selected bioactive natural products: Illustration of strategy and design

Kuniaki Tatsuta*, Seijiro Hosokawa

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

73 Citations (Scopus)

Abstract

A review on the elegant parts and significance of the total synthesis of useful bioactive compounds is presented. Enumerated and discussed are the total syntheses of cochleamycin A, natural products possessing fused aromatic rings, nitrogen-containing polyhydroxy compounds and trichostatin D. The total synthesis using both glycosylation under mitsunobu conditions and stereoselective vinylogous mukaiyama aldol reaction are also discussed.

Original languageEnglish
Pages (from-to)4707-4729
Number of pages23
JournalChemical Reviews
Volume105
Issue number12
DOIs
Publication statusPublished - 2005 Dec

ASJC Scopus subject areas

  • General Chemistry

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