Treatment of a depressive disorder patient with EEG-driven photic stimulation

Hiroaki Kumano*, Harumi Horie, Tomoko Shidara, Tomifusa Kuboki, Hiroyuki Suematsu, Mitsuo Yasushi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


This study examined the effects of electroencephalographic- (EEG-) driven photic stimulation on a case of depressive disorder, as measured by a psychometric test of mood states, EEG parameters, and several autonomic indices. The EEG-driven photic stimulation enhances the alpha rhythm of brain waves using photic signals, the brightness of which is modulated by a subject's own alpha rhythm. The patient was a 37-year-old businessman, who was treated for depression with medication during the 13 months prior to his first visit to our hospital. He underwent two sets of inpatient treatment sessions, comprising first 16 and then 18 treatment sessions. The treatments brought about the following changes: an improvement in general mood state, alpha rhythm increase, cardiac parasympathetic suppression, and increased skin conductance level. In addition, significant correlations between alpha rhythm increase and cardiac parasympathetic suppression or cardiac sympathetic predominance were observed with each inpatient treatment. Significant correlations between alpha rhythm increase, cardiac parasympathetic suppression, or cardiac sympathetic predominance and the improvement of general mood state were also observed. Thus, from these observations, it was concluded that the alpha enhancement induced by EEG-driven photic stimulation produced an improvement in the patient's depressive symptomatology connected with cardiac parasympathetic suppression and sympathetic predominance.

Original languageEnglish
Pages (from-to)323-334
Number of pages12
JournalBiofeedback and Self-Regulation
Issue number4
Publication statusPublished - 1996
Externally publishedYes


  • Alpha rhythm
  • Autonomic nervous system
  • Depression
  • EEG-driven photic stimulation
  • Mood state

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)


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