Abstract
(equation presented) The template-directed syntheses of two [2]rotaxanes, one carrying one and the other two triphenylphosphonium stoppers, have been achieved using a threading-followed-by-stoppering approach. Either one or two benzylic bromide functions-located at the para-positions of dibenzylammonium-based ions, which become encircled by dibenzo[24]crown-8 macrocycles during the initial thermodynamically controlled phases that mark the recognition events-serve as sites for nucleophilic attack by triphenylphosphine during the subsequent kinetic stages that lead to the formation of the two [2]rotaxanes.
| Original language | English |
|---|---|
| Pages (from-to) | 129-132 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 1 |
| Issue number | 1 |
| Publication status | Published - 1999 Jul 15 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Medicine