TY - JOUR
T1 - Ultracompact Compton camera for innovative gamma-ray imaging
AU - Kataoka, J.
AU - Kishimoto, A.
AU - Taya, T.
AU - Mochizuki, S.
AU - Tagawa, L.
AU - Koide, A.
AU - Sueoka, K.
AU - Morita, H.
AU - Maruhashi, T.
AU - Fujieda, K.
AU - Kurihara, T.
AU - Arimoto, M.
AU - Okochi, H.
AU - Katsumi, N.
AU - Kinno, S.
AU - Matsunaga, K.
AU - Ikeda, H.
AU - Shimosegawa, E.
AU - Hatazawa, J.
AU - Ohsuka, S.
AU - Toshito, T.
AU - Kimura, M.
AU - Nagao, Y.
AU - Yamaguchi, M.
AU - Kurita, K.
AU - Kawachi, N.
N1 - Funding Information:
This work was supported by JSPS KAKENHI Grant Number JP15H05720 .
Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2018/12/21
Y1 - 2018/12/21
N2 - A multipixel photon counter (MPPC) features excellent photon-counting capability as a radiation detector. In particular, a two-plane Compton camera consisting of Ce:GAGG scintillators coupled with MPPC arrays has significant application potential owing to its compact size and low weight. For example, the camera can be easily mounted on a commercial drone to identify radiation hot spots from the sky. In Fukushima, we demonstrated that a 137Cs distribution within a 100 m diameter can be mapped correctly within a couple of tens of minutes. The advanced use of the Compton camera is also anticipated in the field of proton therapy. We evaluated an image of 511 keV annihilation gamma-rays emitted from a PMMA phantom irradiated by 200 MeV protons to mimic an in-beam monitor for proton therapy. Finally, we developed an ultracompact Compton camera (weight = 580 g), for 3-D multicolor molecular imaging. In order to demonstrate the performance capabilities of the device, 131I (365 keV), 85SrCl2 (514 keV), and 65ZnCl2 (1116 keV) were injected into a living mouse and the data were taken from 12 angles with a total acquisition time of 2 h. We confirmed that all tracers had accumulated on the target organs of the thyroid, bone, and liver, and that the obtained 3-D image was quantitatively correct with an accuracy of ±20%.
AB - A multipixel photon counter (MPPC) features excellent photon-counting capability as a radiation detector. In particular, a two-plane Compton camera consisting of Ce:GAGG scintillators coupled with MPPC arrays has significant application potential owing to its compact size and low weight. For example, the camera can be easily mounted on a commercial drone to identify radiation hot spots from the sky. In Fukushima, we demonstrated that a 137Cs distribution within a 100 m diameter can be mapped correctly within a couple of tens of minutes. The advanced use of the Compton camera is also anticipated in the field of proton therapy. We evaluated an image of 511 keV annihilation gamma-rays emitted from a PMMA phantom irradiated by 200 MeV protons to mimic an in-beam monitor for proton therapy. Finally, we developed an ultracompact Compton camera (weight = 580 g), for 3-D multicolor molecular imaging. In order to demonstrate the performance capabilities of the device, 131I (365 keV), 85SrCl2 (514 keV), and 65ZnCl2 (1116 keV) were injected into a living mouse and the data were taken from 12 angles with a total acquisition time of 2 h. We confirmed that all tracers had accumulated on the target organs of the thyroid, bone, and liver, and that the obtained 3-D image was quantitatively correct with an accuracy of ±20%.
KW - 3D imaging
KW - Compton camera
KW - Multi-Pixel photon counter (MPPC)
KW - Scintillator
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U2 - 10.1016/j.nima.2017.09.048
DO - 10.1016/j.nima.2017.09.048
M3 - Article
AN - SCOPUS:85030527257
SN - 0168-9002
VL - 912
SP - 1
EP - 5
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
ER -