TY - GEN
T1 - Which Is the best indicator of muscle oxygen extraction during exercise using NIRS?
T2 - Evidence that HHb is not the candidate
AU - Kime, Ryotaro
AU - Fujioka, Masako
AU - Osawa, Takuya
AU - Takagi, Shun
AU - Niwayama, Masatsugu
AU - Kaneko, Yasuhisa
AU - Osada, Takuya
AU - Murase, Norio
AU - Katsumura, Toshihito
PY - 2013
Y1 - 2013
N2 - Recently, deoxygenated hemoglobin (HHb) has been used as one of the most popular indicators of muscle O2 extraction during exercise in the field of exercise physiology. However, HHb may not sufficiently represent muscle O2 extraction, as total hemoglobin (tHb) is not stable during exercise. The purpose of this study was to measure various muscle oxygenation signals during cycle exercise and clarify which is the best indicator of muscle O2 extraction during exercise using NIRS. Ten healthy men performed 6-min cycle exercise at both moderate and heavy work rates. Oxygenated hemoglobin (O2-Hb), HHb, tHb, and muscle tissue oxygen saturation (SmO2) were measured with near-infrared spatial resolved spectroscopy from the vastus lateralis muscle. Skin blood flow (sBF) was also monitored at a site close to the NIRS probe. During moderate exercise, tHb, O2-Hb, and SmO2 displayed progressive increases until the end of exercise. In contrast, HHb remained stable during moderate work rate. sBF remained stable during moderate exercise but showed a progressive decrease at heavy work rate. These results provide evidence that HHb may not sufficiently represent muscle O2 extraction since tHb is not stable during exercise and HHb is insensitive to exercise-induced hyperaemia.
AB - Recently, deoxygenated hemoglobin (HHb) has been used as one of the most popular indicators of muscle O2 extraction during exercise in the field of exercise physiology. However, HHb may not sufficiently represent muscle O2 extraction, as total hemoglobin (tHb) is not stable during exercise. The purpose of this study was to measure various muscle oxygenation signals during cycle exercise and clarify which is the best indicator of muscle O2 extraction during exercise using NIRS. Ten healthy men performed 6-min cycle exercise at both moderate and heavy work rates. Oxygenated hemoglobin (O2-Hb), HHb, tHb, and muscle tissue oxygen saturation (SmO2) were measured with near-infrared spatial resolved spectroscopy from the vastus lateralis muscle. Skin blood flow (sBF) was also monitored at a site close to the NIRS probe. During moderate exercise, tHb, O2-Hb, and SmO2 displayed progressive increases until the end of exercise. In contrast, HHb remained stable during moderate work rate. sBF remained stable during moderate exercise but showed a progressive decrease at heavy work rate. These results provide evidence that HHb may not sufficiently represent muscle O2 extraction since tHb is not stable during exercise and HHb is insensitive to exercise-induced hyperaemia.
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U2 - 10.1007/978-1-4614-7411-1_23
DO - 10.1007/978-1-4614-7411-1_23
M3 - Conference contribution
AN - SCOPUS:84934441778
SN - 9781461472568
VL - 789
T3 - Advances in Experimental Medicine and Biology
SP - 163
EP - 169
BT - Advances in Experimental Medicine and Biology
PB - Springer New York LLC
ER -