Takashi Ohyama

2023

Expression and function of an S1-type nuclease in the digestive fluid of a sundew, Drosera adelae

Yu, M., Arai, N., Ochiai, T. & Ohyama, T., 2023 2月 1, In: Annals of Botany. 131, 2, p. 335-346 12 p.

研究成果: Article › 査読

2021

Cruciform formable sequences within pou5f1 enhancer are indispensable for mouse es cell integrity

Yamamoto, Y., Miura, O. & Ohyama, T., 2021 4月 1, In: International journal of molecular sciences. 22, 7, 3399.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Organ-specific expression and epigenetic traits of genes encoding digestive enzymes in the lance-leaf sundew (Drosera adelae)

Arai, N., Ohno, Y., Jumyo, S., Hamaji, Y. & Ohyama, T., 2021 2月 27, In: Journal of Experimental Botany. 72, 5, p. 1946-1961 16 p.

研究成果: Article › 査読

Open Access

5 被引用数 (Scopus)

2019

A strong structural correlation between short inverted repeat sequences and the polyadenylation signal in yeast and nucleosome exclusion by these inverted repeats

Miura, O., Ogake, T., Yoneyama, H., Kikuchi, Y. & Ohyama, T., 2019 4月 5, In: Current Genetics. 65, 2, p. 575-590 16 p.

研究成果: Article › 査読

Open Access

5 被引用数 (Scopus)

2018

Involvement of the response regulator CtrA in the extracellular DNA production of the marine bacterium Rhodovulum sulfidophilum

Komatsu, H., Yamamoto, J., Suzuki, H., Nagao, N., Hirose, Y., Ohyama, T., Umekage, S. & Kikuchi, Y., 2018, In: Journal of General and Applied Microbiology. 64, 3, p. 103-107 5 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Requirement or exclusion of inverted repeat sequences with cruciform-forming potential in Escherichia coli revealed by genome-wide analyses

Miura, O., Ogake, T. & Ohyama, T., 2018 8月 1, In: Current Genetics. 64, 4, p. 945-958 14 p.

研究成果: Article › 査読

Open Access

8 被引用数 (Scopus)

2017

Magnesium chloride and polyamine can differentiate mouse embryonic stem cells into trophectoderm or endoderm

Tanase, J. I., Yokoo, T., Matsumura, Y., Kinoshita, M., Kikuchi, Y., Suemori, H. & Ohyama, T., 2017 1月 22, In: Biochemical and Biophysical Research Communications. 482, 4, p. 764-770 7 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

2016

Cloning and characterization of a human genomic sequence that alleviates repeat-induced gene silencing

Fukuma, M., Ganmyo, Y., Miura, O., Ohyama, T. & Shimizu, N., 2016 4月, In: PloS one. 11, 4, e0153338.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

2015

Functional analyses of carnivorous plant-specific amino acid residues in S-like ribonucleases

Arai, N., Nishimura, E., Kikuchi, Y. & Ohyama, T., 2015 7月 30, In: Biochemical and Biophysical Research Communications. 465, 1, p. 108-112 5 p., 34351.

研究成果: Article › 査読

4 被引用数 (Scopus)

The gene transfer agent-like particle of the marine phototrophic bacterium Rhodovulum sulfidophilum

Nagao, N., Yamamoto, J., Komatsu, H., Suzuki, H., Hirose, Y., Umekage, S., Ohyama, T. & Kikuchi, Y., 2015 12月 1, In: Biochemistry and Biophysics Reports. 4, p. 369-374 6 p.

研究成果: Article › 査読

Open Access

17 被引用数 (Scopus)

2014

Positions of pluripotency genes and hepatocyte-specific genes in the nucleus before and after mouse ES cell differentiation

Udagawa, K. & Ohyama, T., 2014 3月 24, In: Genetics and Molecular Research. 13, 1, p. 1979-1988 10 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Structural and functional characteristics of S-like ribonucleases from carnivorous plants

Nishimura, E., Jumyo, S., Arai, N., Kanna, K., Kume, M., Nishikawa, J. I., Tanase, J. I. & Ohyama, T., 2014 6月, In: Planta. 240, 1, p. 147-159 13 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

2013

Most methylation-susceptible DNA sequences in human embryonic stem cells undergo a change in conformation or flexibility upon methylation

Shimooka, Y., Nishikawa, J. I. & Ohyama, T., 2013 2月 26, In: Biochemistry. 52, 8, p. 1344-1353 10 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Regions of unusually high flexibility occur frequently in human genomic DNA

Kimura, H., Kageyama, D., Furuya, M., Sugiyama, S., Murata, N. & Ohyama, T., 2013, In: Bioscience, Biotechnology and Biochemistry. 77, 3, p. 612-617 6 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Selective association between nucleosomes with identical DNA sequences

Nishikawa, J. I. & Ohyama, T., 2013 2月, In: Nucleic acids research. 41, 3, p. 1544-1554 11 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

S-like ribonuclease gene expression in carnivorous plants

Nishimura, E., Kawahara, M., Kodaira, R., Kume, M., Arai, N., Nishikawa, J. I. & Ohyama, T., 2013 11月, In: Planta. 238, 5, p. 955-967 13 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

The genome folding mechanism in yeast

Kimura, H., Shimooka, Y., Nishikawa, J. I., Miura, O., Sugiyama, S., Yamada, S. & Ohyama, T., 2013 8月, In: Journal of biochemistry. 154, 2, p. 137-147 11 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

2012

A designed curved DNA sequence remarkably enhances transgene expression from plasmid DNA in mouse liver

Fukunaga, S., Kanda, G., Tanase, J., Harashima, H., Ohyama, T. & Kamiya, H., 2012 8月, In: Gene Therapy. 19, 8, p. 828-835 8 p.

研究成果: Article › 査読

Open Access

12 被引用数 (Scopus)

Nuclear localization of reporter genes activated by curved DNA

Udagawa, K., Kimura, H., Tanabe, H. & Ohyama, T., 2012 4月, In: Journal of Bioscience and Bioengineering. 113, 4, p. 431-437 7 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

2011

Competence of an artificial bent DNA as a transcriptional activator in mouse ES cells

Tanase, J. I., Mitani, T., Udagawa, K., Nishikawa, J. I. & Ohyama, T., 2011 1月, In: Molecular Biology Reports. 38, 1, p. 37-47 11 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

2010

Highly efficient chromatin transcription induced by superhelically curved DNA segments: The underlying mechanism revealed by a yeast system

Tanase, J. I., Morohashi, N., Fujita, M., Nishikawa, J. I., Shimizu, M. & Ohyama, T., 2010 3月 23, In: Biochemistry. 49, 11, p. 2351-2358 8 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

2009

Effects of carriers on transgene expression from plasmids containing a DNA sequence with high histone affinity

Kamiya, H., Fukunaga, S., Ohyama, T. & Harashima, H., 2009 7月 6, In: International Journal of Pharmaceutics. 376, 1-2, p. 99-103 5 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

The human actin-related protein hArp5: Nucleo-cytoplasmic shuttling and involvement in DNA repair

Kitayama, K., Kamo, M., Oma, Y., Matsuda, R., Uchida, T., Ikura, T., Tashiro, S., Ohyama, T., Winsor, B. & Harata, M., 2009 1月 15, In: Experimental Cell Research. 315, 2, p. 206-217 12 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

2008

Genetic information carried in DNA conformation and physical properties

Ohyama, T., 2008 1月 1, In: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 53, 1, p. 1-11 11 p.

研究成果: Article › 査読

2007

Self-assembly of double-stranded DNA molecules at nanomolar concentrations

Inoue, S., Sugiyama, S., Travers, A. A. & Ohyama, T., 2007 1月 9, In: Biochemistry. 46, 1, p. 164-171 8 p.

研究成果: Article › 査読

48 被引用数 (Scopus)

The location of the left-handedly curved DNA sequence affects exogenous DNA expression in vivo

Kamiya, H., Fukunaga, S., Ohyama, T. & Harashima, H., 2007 5月 1, In: Archives of Biochemistry and Biophysics. 461, 1, p. 7-12 6 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

2006

A designed curved DNA segment that is a remarkable activator of eukaryotic transcription

Sumida, N., Nishikawa, J. I., Kishi, H., Amano, M., Furuya, T., Sonobe, H. & Ohyama, T., 2006 12月, In: FEBS Journal. 273, 24, p. 5691-5702 12 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Structural property of DNA that migrates faster in gel electrophoresis, as deduced by CD spectroscopy

Matsugami, A., Tani, K., Ouhashi, K., Uesugi, S., Morita, M., Ohyama, T. & Katahira, M., 2006 6月 1, In: Nucleosides, Nucleotides and Nucleic Acids. 25, 4-6, p. 417-425 9 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

2005

A highly distinctive mechanical property found in the majority of human promoters and its transcriptional relevance

Fukue, Y., Sumida, N., Tanase, J. I. & Ohyama, T., 2005, In: Nucleic acids research. 33, 12, p. 3821-3827 7 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

An S-like ribonuclease gene is used to generate a trap-leaf enzyme in the carnivorous plant Drosera adelae

Okabe, T., Iwakiri, Y., Mori, H., Ogawa, T. & Ohyama, T., 2005 10月 24, In: FEBS Letters. 579, 25, p. 5729-5733 5 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

2004

Core promoter elements of eukaryotic genes have a highly distinctive mechanical property

Fukue, Y., Sumida, N., Nishikawa, J. I. & Ohyama, T., 2004, In: Nucleic acids research. 32, 19, p. 5834-5840 7 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Improvement of the aluminum borate whisker-mediated method of DNA delivery into rice callus

Mizuno, K., Takahashi, W., Ohyama, T., Shimada, T. & Tanaka, O., 2004 3月, In: Plant Production Science. 7, 1, p. 45-49 5 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

2003

Left-handedly curved DNA regulates accessibility to cis-DNA elements in chromatin

Nishikawa, J. I., Amano, M., Fukue, Y., Tanaka, S., Kishi, H., Hirota, Y., Yoda, K. & Ohyama, T., 2003 11月 15, In: Nucleic acids research. 31, 22, p. 6651-6662 12 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

2002

Multimerization of restriction fragments by magnesium-mediated stable base pairing between overhangs: A cause of electrophoretic mobility shift

Tagashira, H., Morita, M. & Ohyama, T., 2002 10月 8, In: Biochemistry. 41, 40, p. 12217-12223 7 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

The curved DNA structure in the 5′-upstream region of the light-responsive genes: Its universality, binding factor and function for cyanobacterial psbA transcription

Asayama, M., Kato, H., Shibato, J., Shirai, M. & Ohyama, T., 2002 11月 1, In: Nucleic acids research. 30, 21, p. 4658-4666 9 p.

研究成果: Article › 査読

Open Access

27 被引用数 (Scopus)

2001

A common feature shared by bent DNA structures locating in the eukaryotic promoter region

Miyano, M., Kawashima, T. & Ohyama, T., 2001, In: Molecular Biology Reports. 28, 1, p. 53-61 9 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Linearization and integration of DNA into cells preferentially occurs at intrinsically curved regions from human LINE-1 repetitive element

Kusakabe, T., Sugimoto, Y., Maeda, T., Nakajima, Y., Miyano, M., Nishikawa, J. I., Tone, S., Kawaguchi, Y., Koga, K. & Ohyama, T., 2001 8月 22, In: Gene. 274, 1-2, p. 271-281 11 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

2000

Conservation of DNA bend sites with identical superhelical twists among the human, mouse, bovine, rabbit and chicken β-globin genes

Wanapirak, C., Onishi, Y., Wada-Kiyama, Y., Ohyama, T. & Kiyama, R., 2000, In: DNA Research. 7, 4, p. 253-259 7 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Isolation of replicational cue elements from a library of bent DNAs of Aspergillus oryzae

Kusakabe, T., Sugimoto, Y., Hirota, Y., Toné, S., Kawaguchi, Y., Koga, K. & Ohyama, T., 2000, In: Molecular Biology Reports. 27, 1, p. 13-19 7 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Quantitation of mRNA using in vitro RNA amplification and Northern hybridization

Toné, S., Kubo, T., Ohyama, T., Kusakabe, T. & Minatogawa, Y., 2000 9月 10, In: Analytical Biochemistry. 284, 2, p. 420-422 3 p.

研究成果: Article › 査読

1999

An intrinsic DNA curvature found in the cyanobacterium Microcystis aeruginosa K-81 affects the promoter activity of rpoD1 encoding a principal sigma factor

Asayama, M., Hayasaka, Y., Kabasawa, M., Shirai, M. & Ohyama, T., 1999 1月 1, In: Journal of biochemistry. 125, 3, p. 460-468 9 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

Influence of highly curved DNA segments on in vivo topology of plasmids

Ohyama, T., Miyano, M. & Sakuma, S., 1999 12月, In: Molecular Biology Reports. 26, 4, p. 269-276 8 p.

研究成果: Article › 査読

1998

In vivo gene transfer to mouse spermatogenic cells by deoxyribonucleic acid injection into seminiferous tubules and subsequent electroporation

Yamazaki, Y., Fujimoto, H., Ando, H., Ohyama, T., Hirota, Y. & Noce, T., 1998 12月, In: Biology of Reproduction. 59, 6, p. 1439-1444 6 p.

研究成果: Article › 査読

98 被引用数 (Scopus)

Mechanism of transcriptional regulation by bent DNA structures

Ohyama, T., 1998 12月 1, In: Seikagaku. 70, 11, p. 1339-1344 6 p.

研究成果: Article › 査読

Suppression of electrophoretic anomaly of bent DNA segments by the structural property that causes rapid migration

Ohyama, T., Tsujibayashi, H., Tagashira, H., Inano, K., Ueda, T., Hirota, Y. & Hashimoto, K., 1998 11月 1, In: Nucleic acids research. 26, 21, p. 4811-4817 7 p.

研究成果: Article › 査読