抄録
The region preceding the beta-lactamase promoter of Escherichia coli plasmid pUC19 has a DNA curvature (curved DNA or bent DNA). Studies using mutant plasmids showed that the curved DNA structure is required for efficient transcription of the beta-lactamase gene and suggested that the requisite shape is a small part of a right-handed coil. Based on these results, the possible functional significance of DNA curvature in transcription will be discussed.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 153-154 |
| ページ数 | 2 |
| ジャーナル | Nucleic acids symposium series |
| 号 | 29 |
| 出版ステータス | Published - 1993 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 医学（全般）