A study of the self-assembling morphology in peptide nanorings and nanotubes

Hajime Okamoto*, Tsutomu Nakanishi, Yukiko Nagai, Tetsuo Yamada, Hiroshi Miyazaki, Kyozaburo Takeda, Yukio Furukawa, Ikuo Obataya, Hisakazu Mihara, Hiroaki Azehara, Wataru Mizutani, Katsushi Hashimoto, Hiroshi Yamaguchi, Yoshiro Hirayama


研究成果: Conference article査読

1 被引用数 (Scopus)


Peptide nanotubes of cyclo[-(D-Ala-L-Gln)4], cyclo[-(D-Ala-L-Gln)3], cyclo[-(D-Cys-L-Gln)3], and cyclo[-(L-Gln)5] have been synthesized and their morphologies have been studied by scanning probe microscopy. The atomic force microscopy displayed several interesting self-assembling forms of these peptide nanotubes. The three D,L-peptides showed not only the straight tubular forms but also the self-assembled bundles. The number and size of observed nanotubes and their bundles were different among those three and also among employed solvents and substrates. On the contrary, the homo-L-peptide of cyclo[-(L-Gln)5] provided meandering nanotubes, which were caused by the symmetry lowering due to the odd number of amino acids. The meandering characteristics also resulted peculiar super-ring forms of the homo-L-peptide nanotubes. Additionally, the scanning tunneling microscopy was performed and high-resolution images of D,L-peptide nanotubes as well as their bundles were obtained.

ジャーナルMaterials Research Society Symposium Proceedings
出版ステータスPublished - 2004
イベント2003 MRS Fall Meeting - Boston, MA, United States
継続期間: 2003 12月 12003 12月 4

ASJC Scopus subject areas

  • 材料科学一般
  • 凝縮系物理学
  • 材料力学
  • 機械工学


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