TY - JOUR
T1 - Advantages of using larger-diameter pinhole collimator for prompt X-ray imaging during irradiation with carbon ions
AU - Yamamoto, Seiichi
AU - Yabe, Takuya
AU - Akagi, Takashi
AU - Yamaguchi, Mitsutaka
AU - Kawachi, Naoki
AU - Kamada, Kei
AU - Yoshikawa, Akira
AU - Kataoka, Jun
N1 - Publisher Copyright:
© 2022 IOP Publishing Ltd and Sissa Medialab.
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Prompt secondary electron bremsstrahlung X-ray (prompt X-ray) imaging using a low-energy X-ray camera is a promising method for observing a beam shape from outside the subject. However, the images measured within short times suffer from statistical noise. Consequently, we performed prompt X-ray imaging with higher sensitivity using a larger-diameter pinhole collimator and compared the results with those of a conventional collimator. Prompt X-ray imaging was conducted during irradiation with pencil beams of 241.5-MeV/n carbon ions to a water phantom. A newly developed X-ray camera with a 4-mm diameter as well as conventional 1.5-mm-diameter pinhole collimators was used for the imaging in list mode, and we compared the prompt X-ray images, energy spectra, and time count rate curves between 1.5-mm-diameter and 4-mm-diameter pinhole collimators. The prompt X-ray images taken with the 4-mm-diameter pinhole collimators had a1/47 times higher sensitivity with 70 % lower offset fractions originating from the prompt gamma photons. Furthermore, the ranges were more precisely estimated with the 4-mm collimator than with the 1.5-mm collimator. The energy spectra showed less contamination by tungsten-characteristic X-rays for the 4-mm pinhole collimator. Even for images measured with 0.1-s intervals, the beam shapes and time count rate curves could be obtained with less statistical noise using the 4-mm-diameter pinhole collimators. The use of the 4-mm-diameter pinhole collimator attached to the X-ray camera had advantages for prompt X-ray imaging with high sensitivity and low background, enabling us to image the beams even with short-Time measurements.
AB - Prompt secondary electron bremsstrahlung X-ray (prompt X-ray) imaging using a low-energy X-ray camera is a promising method for observing a beam shape from outside the subject. However, the images measured within short times suffer from statistical noise. Consequently, we performed prompt X-ray imaging with higher sensitivity using a larger-diameter pinhole collimator and compared the results with those of a conventional collimator. Prompt X-ray imaging was conducted during irradiation with pencil beams of 241.5-MeV/n carbon ions to a water phantom. A newly developed X-ray camera with a 4-mm diameter as well as conventional 1.5-mm-diameter pinhole collimators was used for the imaging in list mode, and we compared the prompt X-ray images, energy spectra, and time count rate curves between 1.5-mm-diameter and 4-mm-diameter pinhole collimators. The prompt X-ray images taken with the 4-mm-diameter pinhole collimators had a1/47 times higher sensitivity with 70 % lower offset fractions originating from the prompt gamma photons. Furthermore, the ranges were more precisely estimated with the 4-mm collimator than with the 1.5-mm collimator. The energy spectra showed less contamination by tungsten-characteristic X-rays for the 4-mm pinhole collimator. Even for images measured with 0.1-s intervals, the beam shapes and time count rate curves could be obtained with less statistical noise using the 4-mm-diameter pinhole collimators. The use of the 4-mm-diameter pinhole collimator attached to the X-ray camera had advantages for prompt X-ray imaging with high sensitivity and low background, enabling us to image the beams even with short-Time measurements.
KW - Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA)
KW - Gamma detectors (scintillators, CZT, HPGe, HgI etc)
KW - Instrumentation for heavy-ion therapy
KW - Instrumentation for particle-beam therapy
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U2 - 10.1088/1748-0221/17/09/P09006
DO - 10.1088/1748-0221/17/09/P09006
M3 - Article
AN - SCOPUS:85138167344
SN - 1748-0221
VL - 17
JO - Journal of Instrumentation
JF - Journal of Instrumentation
IS - 9
M1 - P09006
ER -