AI-Driven Synthetic Biology for Non-Small Cell Lung Cancer Drug Effectiveness-Cost Analysis in Intelligent Assisted Medical Systems

Liu Chang, Jia Wu*, Nour Moustafa, Ali Kashif Bashir, Keping Yu

*この研究の対応する著者

研究成果: Article査読

28 被引用数 (Scopus)

抄録

According to statistics, in the 185 countries' 36 types of cancer, the morbidity and mortality of lung cancer take the first place, and non-small cell lung cancer (NSCLC) accounts for 85% of lung cancer (International Agency for Research on Cancer, 2018), (Bray et al., 2018). Significantly in many developing countries, limited medical resources and excess population seriously affect the diagnosis and treatment of alung cancer patients. The 21st century is an era of life medicine, big data, and information technology. Synthetic biology is known as the driving force of natural product innovation and research in this era. Based on the research of NSCLC targeted drugs, through the cross-fusion of synthetic biology and artificial intelligence, using the idea of bioengineering, we construct an artificial intelligence assisted medical system and propose a drug selection framework for the personalized selection of NSCLC patients. Under the premise of ensuring the efficacy, considering the economic cost of targeted drugs as an auxiliary decision-making factor, the system predicts the drug effectiveness-cost then. The experiment shows that our method can rely on the provided clinical data to screen drug treatment programs suitable for the patient's conditions and assist doctors in making an efficient diagnosis.

本文言語English
ページ(範囲)5055-5066
ページ数12
ジャーナルIEEE Journal of Biomedical and Health Informatics
26
10
DOI
出版ステータスPublished - 2022 10月 1
外部発表はい

ASJC Scopus subject areas

  • コンピュータ サイエンスの応用
  • 健康情報学
  • 電子工学および電気工学
  • 健康情報管理

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