TY - JOUR
T1 - Amphibian prolactins
T2 - Activity in the eft skin transepithelial potential bioassay
AU - Brown, Stephen C.
AU - Stocking Brown, Patricia
AU - Yamamoto, Kazutoshi
AU - Matsuda, Kouhei
AU - Kikuyama, Sakae
PY - 1991
Y1 - 1991
N2 - The effects of purified prolactins isolated from frogs (fPRL; Rana catesbeiana) and newts (nPRL; Cynops pyrrhogaster) were compared with those of ovine prolactin (oPRL) and thyrotropin releasing hormone (TRH) in the eft (Notophthalmus viridescens) skin transepithelial potential (TEP) bioassay. At total doses as low as 0.4 μg/animal, both fPRL and nPRL were as effective as oPRL in reducing eft skin TEP. By contrast, TRH at total doses as high as 400 μg/animal was ineffective in altering eft skin TEP. These data provide the first direct evidence that amphibian PRLs can exert significant physiological control over salamandrid integumental sodium transport.
AB - The effects of purified prolactins isolated from frogs (fPRL; Rana catesbeiana) and newts (nPRL; Cynops pyrrhogaster) were compared with those of ovine prolactin (oPRL) and thyrotropin releasing hormone (TRH) in the eft (Notophthalmus viridescens) skin transepithelial potential (TEP) bioassay. At total doses as low as 0.4 μg/animal, both fPRL and nPRL were as effective as oPRL in reducing eft skin TEP. By contrast, TRH at total doses as high as 400 μg/animal was ineffective in altering eft skin TEP. These data provide the first direct evidence that amphibian PRLs can exert significant physiological control over salamandrid integumental sodium transport.
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U2 - 10.1016/0016-6480(91)90289-I
DO - 10.1016/0016-6480(91)90289-I
M3 - Article
C2 - 1908395
AN - SCOPUS:0025801712
SN - 0016-6480
VL - 82
SP - 1
EP - 7
JO - General and Comparative Endocrinology
JF - General and Comparative Endocrinology
IS - 1
ER -