抄録
The establishment of a cell identification method more accurate than the conventional morphological and cell-type-specific marker analyses has been desired. DNA methylation is related to the gene activity including gene-silencing and is a key mechanism of epigenetics underling cellular differentiaion and development in mammals. Recent studies indicated that there exist unique genomic DNA methylation profiles specific to the cell type. DNA methylation profiles a mechanism for memorizing the set of genes inherent in individual type of cells. In this chapter, we present the methods to analyze DNA methylation status for identifying cells or tissues.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 371-382 |
| ページ数 | 12 |
| ジャーナル | Methods in molecular biology (Clifton, N.J.) |
| 巻 | 289 |
| 出版ステータス | Published - 2005 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 分子生物学
- 遺伝学