Application of dimethylsulphoxide(DMSO) / trifluoroacetic acid(TFA) oxidation to the synthesis of cystine-containing peptide

Akira Otaka; Takaki Koide; Atsuko Shide; Nobutaka Fujii

doi:10.1016/S0040-4039(00)92050-1

Application of dimethylsulphoxide(DMSO) / trifluoroacetic acid(TFA) oxidation to the synthesis of cystine-containing peptide

Akira Otaka^*, Takaki Koide, Atsuko Shide, Nobutaka Fujii

^*この研究の対応する著者

研究成果: Article › 査読

79 被引用数 (Scopus)

抄録

S-protected cysteine derivatives [Cys(Trt), Cys(MBzl), Cys(Dbs), Cys(Bzh)] as well as cysteine were converted to cystine by the action of DMSO / TFA; as examples, two model peptides, oxytocin and an α-human calcitonin gene-related peptide (α-hCGRP), were prepared by this reaction.

本文言語	English
ページ（範囲）	1223-1226
ページ数	4
ジャーナル	Tetrahedron Letters
巻	32
号	9
DOI	https://doi.org/10.1016/S0040-4039(00)92050-1
出版ステータス	Published - 1991 2月 25
外部発表	はい

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/S0040-4039(00)92050-1

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引用スタイル

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