@article{14a050a6dc274b7f969ca79f12da47f3,
title = "Aurantoside L, a New Tetramic Acid Glycoside with Anti-Leishmanial Activity Isolated from the Marine Sponge Siliquariaspongia japonica",
abstract = "A new tetramic acid glycoside, aurantoside L (1), was isolated from the sponge Siliquariaspongia japonica collected at Tsushima Is., Nagasaki Prefecture, Japan. The structure of aurantoside L (1) composed of a tetramic acid bearing a chlorinated polyene system and a trisaccharide part was elucidated using spectral analysis. Aurantoside L (1) showed anti-parasitic activity against L. amazonensis with an IC50 value of 0.74 µM.",
keywords = "Siliquariaspongia japonica, anti-leishmanial activity, aurantosides, marine natural products, marine sponge, mass spectrometry, nuclear magnetic resonance",
author = "Yasumoto Oyadomari and Yasuyuki Goto and Keisuke Suganuma and Kawazu, {Shin Ichiro} and Becking, {Leontine E.} and Nobuhiro Fusetani and Yoichi Nakao",
note = "Publisher Copyright: {\textcopyright} 2024 by the authors.",
year = "2024",
month = apr,
doi = "10.3390/md22040171",
language = "English",
volume = "22",
journal = "Marine Drugs",
issn = "1660-3397",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "4",
}