Aurantoside L, a New Tetramic Acid Glycoside with Anti-Leishmanial Activity Isolated from the Marine Sponge Siliquariaspongia japonica

Yasumoto Oyadomari, Yasuyuki Goto, Keisuke Suganuma, Shin Ichiro Kawazu, Leontine E. Becking, Nobuhiro Fusetani, Yoichi Nakao*

*この研究の対応する著者

研究成果: Article査読

抄録

A new tetramic acid glycoside, aurantoside L (1), was isolated from the sponge Siliquariaspongia japonica collected at Tsushima Is., Nagasaki Prefecture, Japan. The structure of aurantoside L (1) composed of a tetramic acid bearing a chlorinated polyene system and a trisaccharide part was elucidated using spectral analysis. Aurantoside L (1) showed anti-parasitic activity against L. amazonensis with an IC50 value of 0.74 µM.

本文言語English
論文番号171
ジャーナルMarine Drugs
22
4
DOI
出版ステータスPublished - 2024 4月

ASJC Scopus subject areas

  • 薬科学
  • 創薬
  • 薬理学、毒性学および薬学(その他)

フィンガープリント

「Aurantoside L, a New Tetramic Acid Glycoside with Anti-Leishmanial Activity Isolated from the Marine Sponge Siliquariaspongia japonica」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル