Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters

Kenward K.H. Vong; Kazuki Tsubokura; Yoichi Nakao; Tomonori Tanei; Shinzaburo Noguchi; Shinobu Kitazume; Naoyuki Taniguchi; Katsunori Tanaka

doi:10.1039/c7cc01934c

Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters

Kenward K.H. Vong, Kazuki Tsubokura, Yoichi Nakao, Tomonori Tanei, Shinzaburo Noguchi, Shinobu Kitazume, Naoyuki Taniguchi, Katsunori Tanaka^*

^*この研究の対応する著者

先進理工学部

研究成果: Article › 査読

8 被引用数 (Scopus)

抄録

Rapidly growing cancer cells have increased levels of intracellular polyamines compared to normal, healthy tissues. Based on the selective reactivity of glycine propargyl esters, probes were synthesized that show evidence for selective polyamine reactivity, which was then applied for selective cancer cell imaging studies.

本文言語	English
ページ（範囲）	8403-8406
ページ数	4
ジャーナル	Chemical Communications
巻	53
号	60
DOI	https://doi.org/10.1039/c7cc01934c
出版ステータス	Published - 2017

ASJC Scopus subject areas

触媒
電子材料、光学材料、および磁性材料
セラミックおよび複合材料
化学 (全般)
表面、皮膜および薄膜
金属および合金
材料化学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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title = "Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters",

abstract = "Rapidly growing cancer cells have increased levels of intracellular polyamines compared to normal, healthy tissues. Based on the selective reactivity of glycine propargyl esters, probes were synthesized that show evidence for selective polyamine reactivity, which was then applied for selective cancer cell imaging studies.",

author = "Vong, {Kenward K.H.} and Kazuki Tsubokura and Yoichi Nakao and Tomonori Tanei and Shinzaburo Noguchi and Shinobu Kitazume and Naoyuki Taniguchi and Katsunori Tanaka",

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doi = "10.1039/c7cc01934c",

language = "English",

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T1 - Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters

AU - Vong, Kenward K.H.

AU - Tsubokura, Kazuki

AU - Nakao, Yoichi

AU - Tanei, Tomonori

AU - Noguchi, Shinzaburo

AU - Kitazume, Shinobu

AU - Taniguchi, Naoyuki

AU - Tanaka, Katsunori

PY - 2017

Y1 - 2017

N2 - Rapidly growing cancer cells have increased levels of intracellular polyamines compared to normal, healthy tissues. Based on the selective reactivity of glycine propargyl esters, probes were synthesized that show evidence for selective polyamine reactivity, which was then applied for selective cancer cell imaging studies.

AB - Rapidly growing cancer cells have increased levels of intracellular polyamines compared to normal, healthy tissues. Based on the selective reactivity of glycine propargyl esters, probes were synthesized that show evidence for selective polyamine reactivity, which was then applied for selective cancer cell imaging studies.

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U2 - 10.1039/c7cc01934c

DO - 10.1039/c7cc01934c

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AN - SCOPUS:85026328584

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JO - Chemical Communications

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Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters

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ASJC Scopus subject areas

UN SDG

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