@article{7436d75ac1ec4e1daf949e815ed59862,
title = "Catalytic three-component C-C bond forming dearomatization of bromoarenes with malonates and diazo compounds",
abstract = "A Pd-catalyzed dearomative three-component C-C bond formation of bromoarenes with diazo compounds and malonates was developed. Various bromoarenes ranging from benzenoids to azines and heteroles were transformed to the corresponding substituted alicyclic molecules. The key to this reaction is the generation of a benzyl-palladium intermediate, which reacts with malonates to form a Pd-O-enolate species. Strikingly, the present method enabled rapid access to multi-substituted alicycles through subsequent elaboration of dearomatized products.",
author = "Hiroki Kato and Itsuki Musha and Masaaki Komatsuda and Kei Muto and Junichiro Yamaguchi",
note = "Funding Information: This work was supported by JSPS KAKENHI Grant Number JP19H02726 (to J. Y.), JP20H04829 (hybrid catalysis), JP19K15573, and The SATOMI Scholarship Foundation (to K. M.). The Materials Characterization Central Laboratory in Waseda University is acknowledged for HRMS measurement. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",
year = "2020",
month = sep,
day = "7",
doi = "10.1039/d0sc02881a",
language = "English",
volume = "11",
pages = "8779--8784",
journal = "Chemical Science",
issn = "2041-6520",
publisher = "Royal Society of Chemistry",
number = "33",
}