Changes in amygdaloid afterdischarges and kindling effect following olfactory bulbectomy in the rat

Shigenori Watanabe*, Hiroshi Nakanishi, Shigenobu Shibata, Showa Ueki

*この研究の対応する著者

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Changes in the thresholds for afterdischarges and the formation of kindling effect in the medial amygdala following olfactory bulbectomy were investigated in the rat with chronic electrode implants. The threshold for afterdischarges in the amygdala of the olfactory bulbectomized rat (OB rat) was significantly decreased on day 4 after olfactory bulbectomy, however, no significant difference was found between OB and sham operated rats on days 7, 14 and 21 since the threshold in the sham group was also decreased at these periods after the surgery. The formation of kindling effect was remarkably accelerated in the OB rats. In this case, the number of days required to reach the stage 1 (Racine's classification) was significantly shortened. These results suggest that the activity of the medial amygdaloid nucleus is increased following olfactory bulbectomy.

本文言語English
ページ(範囲)687-692
ページ数6
ジャーナルPhysiology and Behavior
28
4
DOI
出版ステータスPublished - 1982 4月
外部発表はい

ASJC Scopus subject areas

  • 実験心理学および認知心理学
  • 行動神経科学

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