TY - JOUR
T1 - Complete structure elucidation of shishididemniols, complex lipids with tyramine-derived tether and two serinol units, from a marine tunicate of the family Didemnidae
AU - Kobayashi, Hirotsugu
AU - Ohashi, Jun'ichiro
AU - Fujita, Tsuyoshi
AU - Iwashita, Takashi
AU - Nakao, Yoichi
AU - Matsunaga, Shigeki
AU - Fusetani, Nobuhiro
PY - 2007/2/16
Y1 - 2007/2/16
N2 - (Chemical Equation Presented) Two new serinolipid derivatives, shishididemniols A (1) and B (2), were isolated as antibacterial constituents of a tunicate of the family Didemnidae. The structure of 1 was elucidated by interpretation of spectral data and the application of the modified Mosher method to 1 and its suitable degradation products. Compound 2 was the chlorohydrin of 1. Compounds 1 and 2 exhibited antibacterial activity against fish pathogenic bacterium Vibrio anguillarum.
AB - (Chemical Equation Presented) Two new serinolipid derivatives, shishididemniols A (1) and B (2), were isolated as antibacterial constituents of a tunicate of the family Didemnidae. The structure of 1 was elucidated by interpretation of spectral data and the application of the modified Mosher method to 1 and its suitable degradation products. Compound 2 was the chlorohydrin of 1. Compounds 1 and 2 exhibited antibacterial activity against fish pathogenic bacterium Vibrio anguillarum.
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U2 - 10.1021/jo062013m
DO - 10.1021/jo062013m
M3 - Article
C2 - 17253745
AN - SCOPUS:33846956843
SN - 0022-3263
VL - 72
SP - 1218
EP - 1225
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 4
ER -
