抄録
Two new potent serine protease inhibitors, cyclotheonamides E2 (3) and E3 (4), have been isolated from a marine sponge of the genus Theonella. Their structures were determined by interpretation of spectral data and chemical degradation studies. They are closely related to the previously reported cyclotheonamide E, from which they differ in the N-acyl group of the alanyl side chain. Cyclotheonamides E, E2, and E3 were more active against thrombin than against trypsin.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 667-670 |
| ページ数 | 4 |
| ジャーナル | Journal of Natural Products |
| 巻 | 61 |
| 号 | 5 |
| DOI | |
| 出版ステータス | Published - 1998 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 分析化学
- 分子医療
- 薬理学
- 薬科学
- 創薬
- 補完代替医療
- 有機化学
UN SDG
この成果は、次の持続可能な開発目標に貢献しています
