Cytotoxic C47-polyacetylene carboxylic acids from a marine sponge Pertrosia sp

Chikane Okamoto; Yoichi Nakao; Tsuyoshi Fujita; Takashi Iwashita; Rob W.M. Van Soest; Nobuhiro Fusetani; Shigeki Matsunaga

doi:10.1021/np0702943

Cytotoxic C₄₇-polyacetylene carboxylic acids from a marine sponge Pertrosia sp

Chikane Okamoto, Yoichi Nakao, Tsuyoshi Fujita, Takashi Iwashita, Rob W.M. Van Soest, Nobuhiro Fusetani, Shigeki Matsunaga^*

^*この研究の対応する著者

研究成果: Article › 査読

18 被引用数 (Scopus)

抄録

Two new polyacetylene carboxylic acids, petroformynic acids B (3) and C (4), were isolated from a marine sponge Pertrosia sp. as cytotoxic constituents. Their structures were determined by interpretation of 2D NMR data and tandem FABMS data. Absolute stereochemistry of 3 was assigned by application of the modified Mosher analysis. Petroformynic acids exhibit moderate cytotoxic activity against P388 cells.

本文言語	English
ページ（範囲）	1816-1819
ページ数	4
ジャーナル	Journal of Natural Products
巻	70
号	11
DOI	https://doi.org/10.1021/np0702943
出版ステータス	Published - 2007 11月
外部発表	はい

ASJC Scopus subject areas

分析化学
分子医療
薬理学
薬科学
創薬
補完代替医療
有機化学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1021/np0702943

他のファイルとリンク

引用スタイル

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