Decarbonylative coupling reaction of aromatic esters

Ryota Isshiki, Toshimasa Okita, Kei Muto, Junichiro Yamaguchi

研究成果: Review article査読

1 被引用数 (Scopus)


Transition metal-catalyzed cross-coupling reactions are a powerful method to form chemical bonds. Conventionally, haloarenes has been used as the most reliable aryl electrophiles in cross- coupling. Recent studies in the cross-coupling arena have enabled to employ unconventional but ubiquitous aryl electrophiles such as phenol and aniline. With this trend of organic synthesis, cross-coupling reactions using aromatic carboxylic acid derivatives such as esters as aryl electrophiles have gained considerable attention as a de novo and efficient method to construct C-C and C-heteroatom bonds. In order to realize this particular transformation, it is important to develop and design transition metal catalysts, those are active toward the scission of ester C-O bonds and decarbonylation. In this review, we describe the progress of catalytic decarbonylative cross- coupling of aromatic esters including chronological aspects and mechanistic considerations.

ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
出版ステータスPublished - 2018

ASJC Scopus subject areas

  • 有機化学


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