抄録
Matrix metalloproteinase (MMP) is known to be involved in chronic inflammation, tumor invasion, and carcinogenesis. To detect MMP-2, we examined the use of field effect transistors (FETs). After the addition of MMP-2 to a fibronectin (FN)- immobilized gate, negative value of FET response was observed, which indicates MMP-2 decreased the amount of negative charges arising from FN molecules. This FET device successfully detected MMP-2 by utilizing degradation of FN on the gate.
本文言語 | English |
---|---|
ページ(範囲) | 825-827 |
ページ数 | 3 |
ジャーナル | Chemistry Letters |
巻 | 41 |
号 | 8 |
DOI | |
出版ステータス | Published - 2012 |
ASJC Scopus subject areas
- 化学一般