TY - CHAP
T1 - Differences in muscle O2 dynamics during treadmill exercise between aerobic capacity-matched overweight and normal-weight adults
AU - Takagi, Shun
AU - Kime, Ryotaro
AU - Midorikawa, Taishi
AU - Niwayama, Masatsugu
AU - Sakamoto, Shizuo
AU - Katsumura, Toshihito
N1 - Funding Information:
Acknowledgments The authors are grateful for revision of this manuscript by Andrea Hope. This work was supported in part by JSPS KAKENHI Grant Number 16 K16487 to Shun Takagi.
Publisher Copyright:
© Springer Nature Switzerland AG 2020.
PY - 2020
Y1 - 2020
N2 - The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were monitored continuously at gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. Significantly higher SmO2 and lower ∆deoxy-Hb and ∆total-Hb were observed in OW compared with NW. Pulmonary O2 uptake (VO2) normalized by fat-free mass was matched between groups. In both groups, peak VO2 was significantly correlated with change in SmO2 and ∆deoxy-Hb. Our findings suggest that both muscle blood volume and deoxygenation were lower in overweight adults, compared to aerobic capacity-matched normal-weight adults. Moreover, lowered muscle O2 extraction was related to peak VO2 in overweight adults, as well as in normal-weight adults.
AB - The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were monitored continuously at gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. Significantly higher SmO2 and lower ∆deoxy-Hb and ∆total-Hb were observed in OW compared with NW. Pulmonary O2 uptake (VO2) normalized by fat-free mass was matched between groups. In both groups, peak VO2 was significantly correlated with change in SmO2 and ∆deoxy-Hb. Our findings suggest that both muscle blood volume and deoxygenation were lower in overweight adults, compared to aerobic capacity-matched normal-weight adults. Moreover, lowered muscle O2 extraction was related to peak VO2 in overweight adults, as well as in normal-weight adults.
KW - Blood volume
KW - Muscle O extraction
KW - Near infrared spectroscopy
KW - Regional difference
KW - Women
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U2 - 10.1007/978-3-030-34461-0_28
DO - 10.1007/978-3-030-34461-0_28
M3 - Chapter
C2 - 31893414
AN - SCOPUS:85077446373
T3 - Advances in Experimental Medicine and Biology
SP - 223
EP - 229
BT - Advances in Experimental Medicine and Biology
PB - Springer
ER -