@article{aa09311e2301430293959e5740bfb0d9,
title = "Direct reductive amination using triethylsilane and catalytic bismuth(III) chloride",
abstract = "Direct reductive amination (DRA) using triethylsilane (TESH) and catalytic bismuth(III) chloride (BiCl3) is described for the first time. The use of TESH and BiCl3 provides easy handling, low cost, non-toxicity, and a mild Lewis acid activity, thereby meeting the demand for green and sustainable chemistry. The developed DRA is highly chemoselective and applicable to less-basic amines. The experimental results of this study revealed that the developed DRA could be catalyzed by BiCl3, which was gradually reduced to Bi(0) or bismuth with a low valency by TESH, but TESCl, Bi(0), and Bi(0) with TESCl catalyzed the DRA to some extent.",
keywords = "Bismuth(0), Bismuth(III) chloride, Catalysis, Direct reductive amination, Triethylsilane",
author = "Takehiko Matsumura and Masahisa Nakada",
note = "Funding Information: This work was financially supported in part by Waseda University Grant for Special Research Projects, The Grant-in-Aid for Scientific Research on Innovative Areas {\textquoteleft}Organic Synthesis based on Reaction Integration, Development of New Methods and Creation of New Substances{\textquoteright} (No. 2105 ), Grant for Scientific Research (B) ( 25293003 ), and Grants for Excellent Graduate Schools (Practical Chemical Wisdom), MEXT, Japan . ",
year = "2014",
month = mar,
day = "5",
doi = "10.1016/j.tetlet.2014.01.132",
language = "English",
volume = "55",
pages = "1829--1834",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd",
number = "10",
}