TY - JOUR
T1 - Effect of activin A and follistatin on the release of pituitary hormones in the bullfrog Rana catesbeiana
AU - Koda, Aya
AU - Yamamoto, Kazutoshi
AU - Uchiyama, Hideho
AU - Vaudry, Hubert
AU - Kikuyama, Sakae
PY - 2000/9
Y1 - 2000/9
N2 - The effects of activin A and follistatin on the release of follicle-stimulating hormone (FSH), luteinizing hormone (LH), growth hormone (GH) and prolactin (PRL) from dispersed pituitary cells of the bullfrogs Rana catesbeiana were studied. Activin A stimulated the release of FSH, GH, and PRL dose-dependently, but not that of LH. Follistatin suppressed the activin-induced FSH, GH, and PRL release, but did not affect the basal secretion of those hormones. From the results obtained in this experiment, together with the previously obtained findings that activin B enhanced the release of FSH, LH, GH, and PRL, we conclude that activin A, in addition to activin B, influences the function of multiple types of pituitary cells in the bullfrog.
AB - The effects of activin A and follistatin on the release of follicle-stimulating hormone (FSH), luteinizing hormone (LH), growth hormone (GH) and prolactin (PRL) from dispersed pituitary cells of the bullfrogs Rana catesbeiana were studied. Activin A stimulated the release of FSH, GH, and PRL dose-dependently, but not that of LH. Follistatin suppressed the activin-induced FSH, GH, and PRL release, but did not affect the basal secretion of those hormones. From the results obtained in this experiment, together with the previously obtained findings that activin B enhanced the release of FSH, LH, GH, and PRL, we conclude that activin A, in addition to activin B, influences the function of multiple types of pituitary cells in the bullfrog.
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M3 - Article
AN - SCOPUS:0034258230
SN - 0289-0003
VL - 17
SP - 971
EP - 975
JO - Zoological Science
JF - Zoological Science
IS - 7
ER -