Effects of lutein-containing supplement on visual acuity and vision-related quality of life in the healthy elderly with subjective visual symptoms

Naobumi Hamadate*, Yoshiyuki Matsumoto, Mami Tasaki, Kayoko Seto, Tetsuro Yamamoto, Hideyo Yamaguchi, Takashi Nakagawa, Etsushi Yamamoto, Sumio Kondo, Masamaru Inaba, Kazunaga Yazawa

*この研究の対応する著者

研究成果: Article査読

抄録

Results Intervention with lutein-containing supplement significantly increased BCVA of both eyes (in within-group comparison), whereas placebo showed a similar effect on only the right-side eye without any effect on the left-side eye. For VRQOL, significant improvement was observed in lutein group but was not in placebo group (in within-group comparison).

Methods: Seventeen each subjects were allocated to placebo (placebo group) and lutein-containing supplement (lutein group). Lutein-containing supplement was taken orally for 6 weeks in a daily dose of 1320 mg (30 mg as lutein). Before the start and after the end of 6-week intervention, all subjects underwent determinations of best-spectacle corrected VA (BOVA) and examinations of VRQOL based on vision symptom VAS scores for efficacy evaluation.

Conclusions Lutein-containing supplement is considered to have beneficial effects on the elderly with complaint of depressed VRQOL.

Objectives: To study the potential of lutein-containing supplement to improve visual acuity (VA) and/or vision-related quality of life (VRQOL) in a randomized, double-blind, placebo-controlled trial with the healthy elderly aged 50 to 70 years who complained of subjective vision symptoms.

本文言語English
ページ(範囲)603-612
ページ数10
ジャーナルJapanese Pharmacology and Therapeutics
42
8
出版ステータスPublished - 2014

ASJC Scopus subject areas

  • 薬理学(医学)
  • 薬理学

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