@article{a84460264c58467398c3e6c9344a2f66,
title = "Eight new cytotoxic metabolites closely related to onnamide A from two marine sponges of the genus Theonella",
abstract = "New cytotoxic compounds 1-7 were isolated along with onnamide A (9) from a marine sponge Theonella sp. collected at Hachijo Island, whereas another Theonella sponge yielded 8. The structures of these compounds were determined by interpretation of the NMR spectral data as well as by comparison of spectral data with those of 9. Six compounds (1-6) were highly cytotoxic against the P388 cell line.",
author = "Shigeki Matsunaga and Nobuhiro Fusetani and Youichi Nakao",
note = "Funding Information: Acknowledgment. We thank Professor P. J. Scheuer of the University of Hawaii for reading the manuscript. We are also indebted to C.Nohara, Central Research Laboratories, Yamanouchi Pharmaceutical Co.,Ltd., for cytotoxicity tests. This work was partially supported by a Grant-in Aid for Scientific Research from the Ministry of Education, Science, and Culture of Japan and by the Fujisawa Foundation.",
year = "1992",
month = sep,
day = "25",
doi = "10.1016/S0040-4020(01)86585-6",
language = "English",
volume = "48",
pages = "8369--8376",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "39",
}
