Enantioselective potential response of a human serum albumin-modified ITO electrode for tryptophan

Mariko Matsunaga; Tsubasa Ueno; Takuya Nakanishi; Tetsuya Osaka

doi:10.1016/j.elecom.2008.09.024

Enantioselective potential response of a human serum albumin-modified ITO electrode for tryptophan

Mariko Matsunaga, Tsubasa Ueno, Takuya Nakanishi, Tetsuya Osaka^*

^*この研究の対応する著者

研究成果: Article › 査読

24 被引用数 (Scopus)

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The present study aims at extending the possibility of utilizing bulky molecules such as proteins for fabricating electrochemical chiral sensors using an indium tin oxide (ITO) electrode. Enantioselective potential response of the human serum albumin (HSA)-modified ITO electrode was observed for tryptophan (Trp) when HSA was immobilized on an ITO electrode surface modified with disuccinimidyl suberate (DSS). In this sensing system, the enantioselective interaction between HSA and Trp is detected through the chemically reactive DSS group immobilized on the ITO electrode.

本文言語	English
ページ（範囲）	1844-1846
ページ数	3
ジャーナル	Electrochemistry Communications
巻	10
号	12
DOI	https://doi.org/10.1016/j.elecom.2008.09.024
出版ステータス	Published - 2008 12月

ASJC Scopus subject areas

電気化学

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10.1016/j.elecom.2008.09.024

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title = "Enantioselective potential response of a human serum albumin-modified ITO electrode for tryptophan",

abstract = "The present study aims at extending the possibility of utilizing bulky molecules such as proteins for fabricating electrochemical chiral sensors using an indium tin oxide (ITO) electrode. Enantioselective potential response of the human serum albumin (HSA)-modified ITO electrode was observed for tryptophan (Trp) when HSA was immobilized on an ITO electrode surface modified with disuccinimidyl suberate (DSS). In this sensing system, the enantioselective interaction between HSA and Trp is detected through the chemically reactive DSS group immobilized on the ITO electrode.",

keywords = "Asymmetric synthesis, Chiral sensor, Enantioselective, Field effect transistor, Indium tin oxide, Protein",

author = "Mariko Matsunaga and Tsubasa Ueno and Takuya Nakanishi and Tetsuya Osaka",

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doi = "10.1016/j.elecom.2008.09.024",

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T1 - Enantioselective potential response of a human serum albumin-modified ITO electrode for tryptophan

AU - Matsunaga, Mariko

AU - Ueno, Tsubasa

AU - Nakanishi, Takuya

AU - Osaka, Tetsuya

PY - 2008/12

Y1 - 2008/12

N2 - The present study aims at extending the possibility of utilizing bulky molecules such as proteins for fabricating electrochemical chiral sensors using an indium tin oxide (ITO) electrode. Enantioselective potential response of the human serum albumin (HSA)-modified ITO electrode was observed for tryptophan (Trp) when HSA was immobilized on an ITO electrode surface modified with disuccinimidyl suberate (DSS). In this sensing system, the enantioselective interaction between HSA and Trp is detected through the chemically reactive DSS group immobilized on the ITO electrode.

AB - The present study aims at extending the possibility of utilizing bulky molecules such as proteins for fabricating electrochemical chiral sensors using an indium tin oxide (ITO) electrode. Enantioselective potential response of the human serum albumin (HSA)-modified ITO electrode was observed for tryptophan (Trp) when HSA was immobilized on an ITO electrode surface modified with disuccinimidyl suberate (DSS). In this sensing system, the enantioselective interaction between HSA and Trp is detected through the chemically reactive DSS group immobilized on the ITO electrode.

KW - Asymmetric synthesis

KW - Chiral sensor

KW - Enantioselective

KW - Field effect transistor

KW - Indium tin oxide

KW - Protein

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U2 - 10.1016/j.elecom.2008.09.024

DO - 10.1016/j.elecom.2008.09.024

M3 - Article

AN - SCOPUS:56249128930

SN - 1388-2481

VL - 10

SP - 1844

EP - 1846

JO - Electrochemistry Communications

JF - Electrochemistry Communications

IS - 12

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Enantioselective potential response of a human serum albumin-modified ITO electrode for tryptophan

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