TY - JOUR
T1 - Enhanced Diagnosis of Pneumothorax with an Improved Real-Time Augmentation for Imbalanced Chest X-rays Data Based on DCNN
AU - Wang, Yaqi
AU - Sun, Lingling
AU - Jin, Qun
N1 - Funding Information:
This work was supported by the National Natural Science Foundation of China (Grant No.KYZ043718114). The authors would like to thank the Radiology Department of the Second Affiliated Hospital, Zhejiang University School of Medicine (ZJU-2), for providing orbital pathology images. The authors also thank Longzhao Yang for the assistance during this work and Dr. Jiawei Wang of the Department of Radiology for providing medical guidance during the experiment.
Publisher Copyright:
© 2004-2012 IEEE.
PY - 2021/5/1
Y1 - 2021/5/1
N2 - Pneumothorax is a common pulmonary disease that can lead to dyspnea and can be life-threatening. X-ray examination is the main means to diagnose this disease. Computer-aided diagnosis of pneumothorax on chest X-ray, as a prerequisite for a timely cure, has been widely studied, but it is still not satisfactory to achieve highly accurate results. In this paper, an image classification algorithm based on the deep convolutional neural network (DCNN) is proposed for high-resolution medical image analysis of pneumothorax X-rays, which features a Network In Network (NIN) for cleaning the data, random histogram equalization data augmentation processing, and a DCNN. The experimental results indicate that the proposed method can effectively increase the correct diagnosis rate of pneumothorax, and the Area under Curve (AUC) of the test verified in the experiment is 0.9844 on ZJU-2 test data and 0.9906 on the ChestX-ray14, respectively. In addition, a large number of atmospheric pleura samples are visualized and analyzed based on the experimental results and in-depth learning characteristics of the algorithm. The analysis results verify the validity of feature extraction for the network. Combined with the results of these two aspects, the proposed X-ray image processing algorithm can effectively improve the classification accuracy of pneumothorax photographs.
AB - Pneumothorax is a common pulmonary disease that can lead to dyspnea and can be life-threatening. X-ray examination is the main means to diagnose this disease. Computer-aided diagnosis of pneumothorax on chest X-ray, as a prerequisite for a timely cure, has been widely studied, but it is still not satisfactory to achieve highly accurate results. In this paper, an image classification algorithm based on the deep convolutional neural network (DCNN) is proposed for high-resolution medical image analysis of pneumothorax X-rays, which features a Network In Network (NIN) for cleaning the data, random histogram equalization data augmentation processing, and a DCNN. The experimental results indicate that the proposed method can effectively increase the correct diagnosis rate of pneumothorax, and the Area under Curve (AUC) of the test verified in the experiment is 0.9844 on ZJU-2 test data and 0.9906 on the ChestX-ray14, respectively. In addition, a large number of atmospheric pleura samples are visualized and analyzed based on the experimental results and in-depth learning characteristics of the algorithm. The analysis results verify the validity of feature extraction for the network. Combined with the results of these two aspects, the proposed X-ray image processing algorithm can effectively improve the classification accuracy of pneumothorax photographs.
KW - Deep convolutional neural network (DCNN)
KW - chest X-rays
KW - imbalanced data
KW - pneumothorax
KW - visualization
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U2 - 10.1109/TCBB.2019.2911947
DO - 10.1109/TCBB.2019.2911947
M3 - Article
C2 - 31021773
AN - SCOPUS:85107507363
SN - 1545-5963
VL - 18
SP - 951
EP - 962
JO - IEEE/ACM Transactions on Computational Biology and Bioinformatics
JF - IEEE/ACM Transactions on Computational Biology and Bioinformatics
IS - 3
M1 - 8693998
ER -