TY - GEN
T1 - Establishment of labo-in-a-microdroplet for azo compound synthesis
AU - Tanaka, Daiki
AU - Sawai, Shunsuke
AU - Sugaya, Takuo
AU - Nozaki, Yoshito
AU - Yoon, Dong Hyun
AU - Isano, Taisuke
AU - Yamagata, Hitoshi
AU - Fujita, Hiroyuki
AU - Sekiguchi, Tetsushi
AU - Akitsu, Takashiro
AU - Shoji, Shuichi
N1 - Funding Information:
This work is partly supported by Canon Medical Systems Corporation and Young business-academia collaboration support program of Nanotechnology Forum. The authors thank for MEXT Nanotechnology Platform Support Project of Waseda University.
Funding Information:
This work is partly supported by Canon Medical Systems Corporation and Young business-academia collaboration support program of NanotechnologFoyumr. ThauehtstohnrafokMErXTNanecohotnyPgloatfomlr Support Project of Waseda University.
Publisher Copyright:
© 2019 CBMS-0001.
PY - 2019
Y1 - 2019
N2 - In this study, microdroplets are regarded as a “small laboratory”, and complex chemical azo compound was firstly synthesis. The synthesis of azo compounds requires accurate pH control. Furthermore, the reaction is accompanied by heat generation. Synthesis applying microdroplets has advantages over temperature control (ice cold→room temperature (23℃)), pH reagent concentration (5.62 molL-1→0.50 molL-1), synthesis time (3,600 sec→4 sec), and recrystallization work was not necessary. The microdroplet rapidly released heat and no side reaction due to heat occurred. The microdroplet method enables accurate pH control and enables highly pure synthesis.
AB - In this study, microdroplets are regarded as a “small laboratory”, and complex chemical azo compound was firstly synthesis. The synthesis of azo compounds requires accurate pH control. Furthermore, the reaction is accompanied by heat generation. Synthesis applying microdroplets has advantages over temperature control (ice cold→room temperature (23℃)), pH reagent concentration (5.62 molL-1→0.50 molL-1), synthesis time (3,600 sec→4 sec), and recrystallization work was not necessary. The microdroplet rapidly released heat and no side reaction due to heat occurred. The microdroplet method enables accurate pH control and enables highly pure synthesis.
KW - Azo-compound
KW - Chemical synthesis
KW - Microdroplet
KW - PH-control
UR - http://www.scopus.com/inward/record.url?scp=85094954686&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85094954686&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85094954686
T3 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
SP - 538
EP - 539
BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PB - Chemical and Biological Microsystems Society
T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Y2 - 27 October 2019 through 31 October 2019
ER -