@inproceedings{43de19891f424f9dbbf199a1f1ddb4f5,
title = "Fast analysis of biological compounds by gradient liquid chromatography using pillar array column",
abstract = "Here we describe fast analysis of biomolecules by newly developed pressure-driven liquid chromatography (LC) on a chip with integration of a gradient elution system. We have reported the fabrication of a gradient elution system using a cross-Tesla mixer on a chip with pillar array columns [1]. In this study, we applied the chip to the analysis of biological compounds, and showed that 10 times faster separation was achieved under gradient elution than under isocratic elution. The retention times under gradient elution conditions were corresponded to the values estimated by semi-empirical equation, which showed that the gradient elution system worked validly.",
keywords = "Aliphatic amines, Fluorescence, NBD-F, Peak width, Pressure driven",
author = "Yanting Song and Masao Noguchi and Katsuya Takatsuki and Tetsushi Sekiguchi and Jun Mizuno and Takashi Funatsu and Shuichi Shoji and Makoto Tsunoda",
year = "2012",
language = "English",
isbn = "9780979806452",
series = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
publisher = "Chemical and Biological Microsystems Society",
pages = "587--589",
booktitle = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
note = "16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 ; Conference date: 28-10-2012 Through 01-11-2012",
}